TCTN1

Gene Symbol	TCTN1
Entrez Gene	79600
Alt Symbol	JBTS13, TECT1
Species	Human
Gene Type	protein-coding
Description	tectonic family member 1
Other Description	tectonic-1
Swissprots	Q8NAE9 Q9H798 Q49A60 Q2MV58 Q96N72 Q6P5X1 Q6UXW2 A8MX11
Accessions	EAW97929 EAW97930 EAW97931 EAW97932 Q2MV58 AK024780 BAB15000 AK055891 BAB71036 AK092775 BAC03973 AK128417 AK295514 BAG58431 AK301732 BAH13543 AY358184 AAQ88551 BC030993 AAH30993 BC033811 AAH33811 BC040113 AAH40113 BC044885 BC062611 AAH62611 BP275624 CA419765 DN997186 DQ278868 ABB90560 XM_005253934 XP_005253991 XM_005253935 XP_005253992 XM_005253936 XP_005253993 XM_006719594 XP_006719657 XM_006719595 XP_006719658 XM_006719596 XP_006719659 XM_006719597 XP_006719660 XM_006719598 XP_006719661 XM_006719599 XP_006719662 XM_006719600 XP_006719663 XM_011538733 XP_011537035 XM_011538734 XP_011537036 XM_011538735 XP_011537037 XM_011538736 XP_011537038 XM_011538737 XP_011537039 XM_011538738 XP_011537040 XM_011538739 XP_011537041 XR_243021 XR_243022 XR_429116 XR_944717 NM_001082537 NP_001076006 NM_001082538 NP_001076007 NM_001173975 NP_001167446 NM_001173976 NP_001167447 NM_024549 NP_078825
Function	Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Secreted {ECO:0000305}. Note=Despite the presence of a signal sequence, the full length protein might not be secreted. Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TCTN1 Antibody Blocking Peptide - LS-E30958 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TCTN1 Blocking Peptide - NBP1-77182PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TCTN1 Peptide - GTX85178-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

TCTN1 Blocking Peptide - 33R-10624 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TCTN1 Blocking Peptide - 33R-10625 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TCTN1 Peptide - 5833P from ProSci Category Peptide Species Human

TCTN1 fusion protein - ag6099 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Tectonic-1(TCTN1) - CSB-YP642681HU CSB-EP642681HU CSB-BP642681HU CSB-MP642681HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Tectonic-1 (transcript variant 2) - TP309467 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Tectonic-1 (TCTN1), Recombinant Protein - MBS1305433 from MyBioSource Category Protein Prices $1,360.00, $1,360.00, $1,580.00, $1,580.00, $2,265.00, $2,265.00, $2,730.00, $2,730.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TCTN1, Peptide - MBS843653 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

TCTN1, Peptide - MBS843915 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

TCTN1 Recombinant Protein Antigen - NBP1-83624PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TCTN1 Recombinant Protein Antigen - NBP1-83623PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TECT1-Antibody-Center-Blocking-Peptide - BP4974c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TCTN1 Peptide, Human - M34GP15752H from Creative Peptides Category Peptide Source Synthetic. Species Human

TCTN1 Antibody - SH-A16204 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

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