| Gene Symbol |
SMCP
|
| Entrez Gene |
4184
|
| Alt Symbol |
HSMCSGEN1, MCS, MCSP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sperm mitochondria-associated cysteine-rich protein
|
| Other Description |
mitochondrial capsule selenoprotein|sperm mitochondrial-associated cysteine-rich protein
|
| Swissprots |
Q96A42 P49901
|
| Accessions |
CAD56487 EAW53361 P49901 AK312020 BAG34957 BC014593 AAH14593 BC016744 AAH16744 DQ890788 ABM81714 DQ893944 ABM84870 X89960 CAA62000 NM_030663 NP_109588
|
| Function |
Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Mitochondrion membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis. {ECO:0000250}.
|
| Tissue Specificity |
Testis. Is selectively expressed in the spermatids of seminiferous tubules. {ECO:0000269|PubMed:8833144}.
|
![Western Blot: SMCP Overexpression Lysate (Adult Normal) [NBL1-16238] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SMCP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1073_SMCP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16238-img0002.jpg)