Gene Symbol | SMCP |
---|---|
Entrez Gene | 4184 |
Alt Symbol | HSMCSGEN1, MCS, MCSP |
Species | Human |
Gene Type | protein-coding |
Description | sperm mitochondria-associated cysteine-rich protein |
Other Description | mitochondrial capsule selenoprotein|sperm mitochondrial-associated cysteine-rich protein |
Swissprots | Q96A42 P49901 |
Accessions | CAD56487 EAW53361 P49901 AK312020 BAG34957 BC014593 AAH14593 BC016744 AAH16744 DQ890788 ABM81714 DQ893944 ABM84870 X89960 CAA62000 NM_030663 NP_109588 |
Function | Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Mitochondrion membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Becomes associated with the spermatid mitochondrion capsule at step 16 of spermatogenesis. {ECO:0000250}. |
Tissue Specificity | Testis. Is selectively expressed in the spermatids of seminiferous tubules. {ECO:0000269|PubMed:8833144}. |
SMCP CRISPR/Cas9 KO Plasmid (h) - sc-410881 from Santa Cruz Biotechnology
|
||||||||
SMCP HDR Plasmid (h) - sc-410881-HDR from Santa Cruz Biotechnology
|
||||||||
SMCP Double Nickase Plasmid (h) - sc-410881-NIC from Santa Cruz Biotechnology
|
||||||||
SMCP Double Nickase Plasmid (h2) - sc-410881-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SMCP CRISPR Activation Plasmid (h) - sc-410881-ACT from Santa Cruz Biotechnology
|
||||||||
SMCP CRISPR Activation Plasmid (h2) - sc-410881-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SMCP Lentiviral Activation Particles (h) - sc-410881-LAC from Santa Cruz Biotechnology
|
||||||||
SMCP Lentiviral Activation Particles (h2) - sc-410881-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SMCP siRNA (h) - sc-78562 from Santa Cruz Biotechnology
|
||||||||
SMCP shRNA Plasmid (h) - sc-78562-SH from Santa Cruz Biotechnology
|
||||||||
SMCP shRNA (h) Lentiviral Particles - sc-78562-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU053021 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19781 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19781 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02701 from Sigma-Aldrich
|
||||||||
SMCP siRNA (Human) - CRH2846 from Cohesion Biosciences
|
||||||||
SMCP - MBS8239615 from MyBioSource
|
||||||||
shRNA set against Human SMCP (NM_030663.2) - SHH413324 from Creative biogene
|
||||||||
shRNA set against Human SMCP(NM_030663.2) - SHH222072 from Creative biogene
|
||||||||
SMCP shRNA Plasmid (Human) - CHH2846 from Cohesion Biosciences
|
||||||||
SMCP miRNA 3'UTR clone - MiUTR1H-09657 from Creative biogene
|