Gene Symbol | CLEC2D |
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Entrez Gene | 29121 |
Alt Symbol | CLAX, LLT1, OCIL |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 2, member D |
Other Description | C-type lectin domain family 2 member D|C-type lectin related f|C-type lectin superfamily 2, member D|LLT-1|lectin-like NK cell receptor|lectin-like transcript 1|osteoclast inhibitory lectin |
Swissprots | Q6YID5 D6CI40 Q9UHP7 D6CI39 Q9HD37 D6CI41 Q8WUP7 Q9HD38 |
Accessions | AAN59996 EAW96114 EAW96118 EAW96119 Q9UHP7 AF133299 AAF22159 AF285087 AAG00514 AF285088 AAG00515 AF285089 AAG00516 AK310150 AK310554 AK313554 BC019883 AAH19883 BC063128 BC094859 AAH94859 BU929933 CB958277 DA814760 DB111977 DB124897 FN813349 CBL81070 FN813350 CBL81071 FN813351 CBL81072 KF958454 AHM10384 KF958455 AHM10385 KF958456 AHM10386 KF958457 AHM10387 KF958458 AHM10388 KF958459 AHM10389 KF971856 AHK61105 KF971857 AHK61106 KF971858 AHK61107 KF971859 AHK61108 NM_001004419 NP_001004419 NM_001197317 NP_001184246 NM_001197318 NP_001184247 NM_001197319 NP_001184248 NM_013269 NP_037401 NR_036693 NM_001004420 |
Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans. {ECO:0000269|PubMed:14753741, ECO:0000269|PubMed:15104121, ECO:0000269|PubMed:16339513}. |
Subcellular Location | Isoform 4: Endoplasmic reticulum. |
Tissue Specificity | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. {ECO:0000269|PubMed:10541800, ECO:0000269|PubMed:20843815}. |
CLEC-2D (N-12) - sc-103435 from Santa Cruz Biotechnology
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CLEC-2D (H-40) - sc-367104 from Santa Cruz Biotechnology
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CLEC-2D (T-13) - sc-103436 from Santa Cruz Biotechnology
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Anti-CLEC2D antibody - ab197341 from Abcam
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Anti-CLEC2D antibody - ab111105 from Abcam
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Anti-CLEC2D antibody - ab76529 from Abcam
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Anti-CLEC2D antibody - ab57073 from Abcam
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Anti-CLEC2D antibody - ab172532 from Abcam
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Anti-CLEC2D antibody [EPR6584(2)] - ab151738 from Abcam
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Anti-CLEC2D antibody - C-terminal - ab186438 from Abcam
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, AP) - LS-C233934 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, Biotin) - LS-C233932 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, APC) - LS-C233931 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, FITC) - LS-C233933 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, PE) - LS-C233939 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137, Azide-free, HRP) - LS-C249693 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody - LS-C309927 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137) - LS-C320438 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa2-18, clone 166C1309) - LS-C574 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (aa109-137) - LS-C159365 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (C-Terminus) - LS-C205743 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (clone 4C7) IHC-plus™ - LS-B6225 from LifeSpan Bioscience
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Anti-CLEC2D / OCIL / LLT1 Antibody (Internal) IHC-plus™ - LS-B3958 from LifeSpan Bioscience
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OCIL/CLEC2d Antibody (4C7) - H00029121-M01 from Novus Biologicals
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OCIL/CLEC2d Antibody - AF3480 from Novus Biologicals
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