Gene Symbol | CLEC2D |
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Entrez Gene | 29121 |
Alt Symbol | CLAX, LLT1, OCIL |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin domain family 2, member D |
Other Description | C-type lectin domain family 2 member D|C-type lectin related f|C-type lectin superfamily 2, member D|LLT-1|lectin-like NK cell receptor|lectin-like transcript 1|osteoclast inhibitory lectin |
Swissprots | Q6YID5 D6CI40 Q9UHP7 D6CI39 Q9HD37 D6CI41 Q8WUP7 Q9HD38 |
Accessions | AAN59996 EAW96114 EAW96118 EAW96119 Q9UHP7 AF133299 AAF22159 AF285087 AAG00514 AF285088 AAG00515 AF285089 AAG00516 AK310150 AK310554 AK313554 BC019883 AAH19883 BC063128 BC094859 AAH94859 BU929933 CB958277 DA814760 DB111977 DB124897 FN813349 CBL81070 FN813350 CBL81071 FN813351 CBL81072 KF958454 AHM10384 KF958455 AHM10385 KF958456 AHM10386 KF958457 AHM10387 KF958458 AHM10388 KF958459 AHM10389 KF971856 AHK61105 KF971857 AHK61106 KF971858 AHK61107 KF971859 AHK61108 NM_001004419 NP_001004419 NM_001197317 NP_001184246 NM_001197318 NP_001184247 NM_001197319 NP_001184248 NM_013269 NP_037401 NR_036693 NM_001004420 |
Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans. {ECO:0000269|PubMed:14753741, ECO:0000269|PubMed:15104121, ECO:0000269|PubMed:16339513}. |
Subcellular Location | Isoform 4: Endoplasmic reticulum. |
Tissue Specificity | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. {ECO:0000269|PubMed:10541800, ECO:0000269|PubMed:20843815}. |
Human CLEC2D peptide - ab93749 from Abcam
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Human CLEC2D protein fragment - ab132623 from Abcam
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Human CLEC2D protein fragment - ab140047 from Abcam
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CLEC2D / OCIL / LLT1 Antibody Blocking Peptide - LS-E6268 from LifeSpan Bioscience
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OCIL/CLEC2d Recombinant Protein - H00029121-P01 from Novus Biologicals
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Recombinant Human OCIL/CLEC2d Protein - NBP2-22966 from Novus Biologicals
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CLEC2D-Antibody-Center-Blocking-Peptide - BP18951c from Abgent, a WuXi AppTec company
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CLEC2D protein (His tag) - 80R-2642 from Fitzgerald
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CLEC2D (60-191, His-tag) - AR50762PU-N from Acris Antibodies
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CLEC2D (60-191, His-tag) - AR50762PU-S from Acris Antibodies
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CLEC2D - H00029121-P01-10 from Acris Antibodies
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CLEC2D - H00029121-P01-25 from Acris Antibodies
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CLEC2D, 60-191aa Human, His tag, E.coli - 01-P1938 from ARP American Research Products
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CLEC2D fusion protein - ag3862 from Proteintech Group
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Recombinant Human C-type lectin domain family 2 member D(CLEC2D) - CSB-YP883401HU CSB-EP883401HU CSB-BP883401HU CSB-MP883401HU from Cusabio
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CLEC2D, 60-191aa, Human, His tag, E.coli (Denatured) - ATGP1938 from ATGen
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CLEC2D (transcript variant 2) - TP321680 from Acris Antibodies
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C-type lectin domain family 2 member D (CLEC2D), Recombinant Protein - MBS1287577 from MyBioSource
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OCIL/CLEC2d Recombinant Protein Antigen - NBP1-84455PEP from Novus Biologicals
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CLEC2D Peptide, Human - M34GP03263H from Creative Peptides
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CLEC2D - PAT-81938-1 from Nordic BioSite
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CLEC2D - PAT-81938-2 from Nordic BioSite
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CLEC2D, Recombinant Protein - MBS204937 from MyBioSource
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