| Gene Symbol |
LMOD3
|
| Entrez Gene |
56203
|
| Alt Symbol |
NEM10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leiomodin 3 (fetal)
|
| Other Description |
leiomodin, fetal form|leiomodin-3
|
| Swissprots |
B4DT85 Q8IUK4 Q5JPG6 Q0VAK6 Q0JTT2 Q96LS4
|
| Accessions |
EAW65471 EAW65472 Q0VAK6 AI014510 AK057852 BAB71596 AK096900 AK300096 BAG61897 AL832033 AL832709 CAI46110 AM393202 CAL38080 BC017925 BC039202 AAH39202 BC121019 AAI21020 DA563370 NM_001304418 NP_001291347 NM_198271 NP_938012
|
| Function |
Essential for the organization of sarcomeric actin thin filaments in skeletal muscle (PubMed:25250574). Increases the rate of actin polymerization (PubMed:25250574). {ECO:0000269|PubMed:25250574}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:25250574}. Note=Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end. {ECO:0000269|PubMed:25250574}.
|
| Tissue Specificity |
Expressed in cardiac and at higher levels in skeletal muscles (at protein level). {ECO:0000269|PubMed:25250574}.
|
![Western Blot: LMOD3 Overexpression Lysate (Adult Normal) [NBP2-04715] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LMOD3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5024_LMOD3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04715-img0001.jpg)