Gene Symbol |
CSPG5
|
Entrez Gene |
10675
|
Alt Symbol |
NGC
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chondroitin sulfate proteoglycan 5 (neuroglycan C)
|
Other Description |
acidic leucine-rich EGF-like domain-containing brain protein|chondroitin sulfate proteoglycan 5
|
Swissprots |
O95196 Q71M40 Q71M39
|
Accessions |
EAW64829 EAW64830 O95196 AF059274 AAC69612 AF461087 AAQ04774 AF461088 AAQ04775 AF461089 AAQ04776 AI368601 AI989800 AK094639 AK294621 BAH11826 AW003890 BC041406 BC111583 AAI11584 BM674119 BU732090 DB636494 NM_001206942 NP_001193871 NM_001206943 NP_001193872 NM_001206944 NP_001193873 NM_001206945 NP_001193874 NM_006574 NP_006565
|
Function |
May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. {ECO:0000269|PubMed:15358134}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. {ECO:0000250}.
|
Tissue Specificity |
Restricted to brain (at protein level). {ECO:0000269|PubMed:9950058}.
|