Gene Symbol | CSPG5 |
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Entrez Gene | 10675 |
Alt Symbol | NGC |
Species | Human |
Gene Type | protein-coding |
Description | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
Other Description | acidic leucine-rich EGF-like domain-containing brain protein|chondroitin sulfate proteoglycan 5 |
Swissprots | O95196 Q71M40 Q71M39 |
Accessions | EAW64829 EAW64830 O95196 AF059274 AAC69612 AF461087 AAQ04774 AF461088 AAQ04775 AF461089 AAQ04776 AI368601 AI989800 AK094639 AK294621 BAH11826 AW003890 BC041406 BC111583 AAI11584 BM674119 BU732090 DB636494 NM_001206942 NP_001193871 NM_001206943 NP_001193872 NM_001206944 NP_001193873 NM_001206945 NP_001193874 NM_006574 NP_006565 |
Function | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. {ECO:0000269|PubMed:15358134}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. {ECO:0000250}. |
Tissue Specificity | Restricted to brain (at protein level). {ECO:0000269|PubMed:9950058}. |
Neuroglycan C CRISPR/Cas9 KO Plasmid (h) - sc-416383 from Santa Cruz Biotechnology
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Neuroglycan C HDR Plasmid (h) - sc-416383-HDR from Santa Cruz Biotechnology
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Neuroglycan C Double Nickase Plasmid (h) - sc-416383-NIC from Santa Cruz Biotechnology
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Neuroglycan C Double Nickase Plasmid (h2) - sc-416383-NIC-2 from Santa Cruz Biotechnology
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Neuroglycan C CRISPR Activation Plasmid (h) - sc-416383-ACT from Santa Cruz Biotechnology
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Neuroglycan C CRISPR Activation Plasmid (h2) - sc-416383-ACT-2 from Santa Cruz Biotechnology
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Neuroglycan C Lentiviral Activation Particles (h) - sc-416383-LAC from Santa Cruz Biotechnology
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Neuroglycan C Lentiviral Activation Particles (h2) - sc-416383-LAC-2 from Santa Cruz Biotechnology
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Neuroglycan C siRNA (h) - sc-62681 from Santa Cruz Biotechnology
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Neuroglycan C shRNA Plasmid (h) - sc-62681-SH from Santa Cruz Biotechnology
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Neuroglycan C shRNA (h) Lentiviral Particles - sc-62681-V from Santa Cruz Biotechnology
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Neuroglycan C/CSPG5 RNAi - H00010675-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6660 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6660 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02905 from Sigma-Aldrich
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CSPG5 siRNA (Human) - CRH7281 from Cohesion Biosciences
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CSPG5 - MBS8214378 from MyBioSource
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shRNA set against Human CSPG5 (NM_006574.3) - SHH270581 from Creative biogene
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shRNA set against Human CSPG5(NM_006574.3) - SHG204283 from Creative biogene
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Human CSPG5 siRNA - orb267783 from Biorbyt
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CSPG5 shRNA Plasmid (Human) - CHH7281 from Cohesion Biosciences
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CSPG5 miRNA 3'UTR clone - MiUTR1H-02487 from Creative biogene
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