COL13A1

Gene Symbol COL13A1
Entrez Gene 1305
Alt Symbol COLXIIIA1
Species Human
Gene Type protein-coding
Description collagen, type XIII, alpha 1
Other Description collagen alpha-1(XIII) chain
Swissprots Q13996 A6NFR5 Q7KZ49 Q13993 Q9NQ52 E7EWL8 Q5TAT6 Q13995 Q13992 Q13994 B9EGD2 Q5TAT5 Q7KZ33 Q99228 Q5TAT4
Accessions AAA51987 AAA51988 AAA51989 AAA51990 AAA51991 AAA52754 AAD48082 EAW54333 EAW54334 EAW54335 EAW54336 EAW54337 EAW54338 EAW54339 EAW54340 EAW54341 EAW54342 EAW54343 EAW54344 EAW54345 EAW54346 EAW54347 EAW54348 EAW54349 EAW54350 EAW54351 EAW54352 EAW54353 EAW54354 EAW54355 EAW54356 EAW54357 EAW54358 EAW54359 EAW54360 EAW54361 EAW54362 EAW54363 EAW54364 EAW54365 EAW54366 EAW54367 EAW54368 EAW54369 EAW54370 Q5TAT6 AI741175 AJ293624 CAC00688 AK124476 BC136385 AAI36386 BC139913 BM744248 BY796799 CN297094 M15524 AAA52048 M33653 AAA52047 M59217 AAA51685 XM_011539292 XP_011537594 XM_011539293 XP_011537595 XM_011539294 XP_011537596 XM_011539295 XP_011537597 XM_011539296 XP_011537598 NM_001130103 NP_001123575 NM_080798 NP_542988 NM_080800 NP_542990 NM_080801 NP_542991 NM_080802 NP_542992 NM_080805 NP_542995 NM_005203 NM_080799 NM_080803 NM_080804 NM_080806 NM_080807 NM_080808 NM_080809 NM_080810 NM_080811 NM_080812 NM_080813 NM_080814 NM_080815
Function Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. {ECO:0000250|UniProtKB:Q9R1N9, ECO:0000269|PubMed:10865988, ECO:0000269|PubMed:11956183}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:11013208}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9R1N9, ECO:0000269|PubMed:11013208}.
Tissue Specificity Widely expressed in both fetal and adult ocular tissues (at protein level). In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. {ECO:0000269|PubMed:10865988, ECO:0000269|PubMed:8246446}.
Top Pathways Protein digestion and absorption

COL13A1 (G-13) - sc-167513 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

COL13A1 (N-14) - sc-167514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
COL13A1 (N-14): sc-167514. Western blot analysis of COL13A1 expression in NCI-H292 (A), HUV-EC-C (B), HeLa (C), JAR (D) and Y79 (E) whole cell lysates.

Anti-COL13A1 antibody - ab111397 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-COL13A1 antibody (ab111397) at 1/100 dilution + NCI-H292 cell lysate at 35 µg

Anti-COL13A1 / Collagen XIII Antibody (aa107-565) - LS-C182824 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody - LS-C143709 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, AP) - LS-C208505 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, APC) - LS-C208506 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, Biotin) - LS-C208507 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, Azide-free, HRP) - LS-C208509 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, FITC) - LS-C208508 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa53-81) - LS-C329399 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa60-89, PE) - LS-C208510 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COL13A1 / Collagen XIII Antibody (aa641-690) - LS-C198821 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using Collagen XIII alpha1 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-COL13A1 / Collagen XIII Antibody (C-Terminus) - LS-C345655 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CODA1 Antibody with human 786-0 Whole Cell lysate.

Collagen XIII alpha 1 Antibody - AF4627 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of HT1080 human fibrosarcoma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Mouse Collagen XIII alpha 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4627) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Collagen XIII alpha 1 at approximately 85‑95 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Collagen XIII alpha 1 Antibody (584718) - MAB6346 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 584718
Immunohistochemistry Collagen XIII alpha 1 Antibody (584718)

Collagen XIII alpha 1 Antibody - AF6346 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of HUVEC human umbilical vein endothelial cells. PVDF Membrane was probed with 1 µg/mL of Human Collagen XIII alpha 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6346) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). Two specific bands were detected for Collagen XIII a1 at approximately 100 and 110 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Collagen XIII alpha 1 Antibody - NBP2-13854 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Collagen XIII alpha 1 Antibody [NBP2-13854] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4

Anti-COL13A1 (251-265) antibody produced in rabbit - C3998 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human COL13A1 was separated on SDS-PAGE, blotted with Anti-COL13A1 (251-265) (<B>Cat. No. C3998</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-COL13A1 (438-450) antibody produced in rabbit - C4123 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human COL13A1 was separated on SDS-PAGE, blotted with Anti-COL13A1 (438-450) (<B>Cat. No. C4123</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500

Anti-COL13A1 antibody produced in rabbit - HPA050392 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COL13A1:<B>Cat. No. HPA050392</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.

CODA1 Antibody - C-terminal region (ARP73935_P050) - ARP73935_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

COL13A1-Antibody-N-term - AP11858a from Abgent, a WuXi AppTec company

Host Rabbit
Clonality Polyclonal
COL13A1 Antibody (N-term) (Cat. #AP11858a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the COL13A1 antibody detected the COL13A1 protein (arrow).

Human Collagen XIII alpha 1 Antibody - MAB6346 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 584718
Collagen XIII a1 in Human Placenta. Collagen XIII a1 was detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human Collagen XIII a1 Monoclonal Antibody (Catalog # MAB6346) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002 ) and counterstained with hematoxylin (blue). Specific staining was localized to basement membrane. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .

Human Collagen XIII alpha 1 MAb (Clone 584718), Mouse IgG2B - MAB6346-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 584718
Collagen XIII  alpha 1 in Human Placenta.Collagen XIII  alpha 1 was detected in immersion fixed paraffin-embedded sections of human placenta using Mouse Anti-Human Collagen XIII  alpha 1 Monoclonal Antibody (Catalog # MAB6346) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to basement membrane. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
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