| Gene Symbol | HLA-E |
|---|---|
| Entrez Gene | 3133 |
| Alt Symbol | EA1.2, EA2.1, HLA-6.2, MHC, QA1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | major histocompatibility complex, class I, E |
| Other Description | HLA class I histocompatibility antigen, E alpha chain|HLA class I histocompatibility antigen, alpha chain E|MHC HLA-E alpha-1|MHC HLA-E alpha-2.1|MHC class I antigen E|lymphocyte antigen |
| Swissprots | Q9GIY8 Q9BT83 P13747 Q9GIY7 Q30169 |
| Accessions | AAA36305 AAA59835 AAA63223 AAA63224 AAA63225 AAF25962 AAM74969 AAM74970 AAM74971 AAM74972 AAM74973 AAM74974 AAM74975 AAM74976 AAM74977 AAM74978 AAT73207 AAT73208 AAT73209 AAT73210 AAT73211 AAT73212 AAT73213 AAT73214 AAT73215 AAT73216 AAT73217 AAT73218 AAT73219 AAT73220 AAT73221 AAT73222 AAT73223 AAT73224 ADN38247 AFK32127 AGO87012 AGS13698 AHG55088 AHG55089 BAB63328 BAC54925 BAE78609 BAF31260 CAA05526 CAA05527 CAA46099 CAG29392 CDX10595 CDX10596 CRI06750 CRI06751 CRI06752 CRI06753 EAX03290 EAX03291 EAX03292 P13747 AB209870 BAD93107 AJ293263 CAC07212 AJ293264 CAC07213 AK098434 AK225048 AK292391 BAF85080 AK296822 BAG59393 AK298695 BAG60853 AK300906 BAG62542 AK301125 BAG62719 AK314411 AK316327 BAH14698 AY216681 AAO37688 AY221103 AAO34408 BC002578 AAH02578 BC004297 AAH04297 BC040479 AAH40479 BM791769 BX538084 CAD98008 CA439575 CD366016 DA832616 DQ891891 ABM82817 DQ895077 ABM86003 L78455 L78934 M20022 AAA52655 M31183 AAA57146 X56841 CAA40172 X64879 CAA46098 NM_005516 NP_005507 |
| Function | Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Natural killer cell mediated cytotoxicity, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Viral carcinogenesis, Herpes simplex infection |