HLA-E

Gene Symbol HLA-E
Entrez Gene 3133
Alt Symbol EA1.2, EA2.1, HLA-6.2, MHC, QA1
Species Human
Gene Type protein-coding
Description major histocompatibility complex, class I, E
Other Description HLA class I histocompatibility antigen, E alpha chain|HLA class I histocompatibility antigen, alpha chain E|MHC HLA-E alpha-1|MHC HLA-E alpha-2.1|MHC class I antigen E|lymphocyte antigen
Swissprots Q9GIY8 Q9BT83 P13747 Q9GIY7 Q30169
Accessions AAA36305 AAA59835 AAA63223 AAA63224 AAA63225 AAF25962 AAM74969 AAM74970 AAM74971 AAM74972 AAM74973 AAM74974 AAM74975 AAM74976 AAM74977 AAM74978 AAT73207 AAT73208 AAT73209 AAT73210 AAT73211 AAT73212 AAT73213 AAT73214 AAT73215 AAT73216 AAT73217 AAT73218 AAT73219 AAT73220 AAT73221 AAT73222 AAT73223 AAT73224 ADN38247 AFK32127 AGO87012 AGS13698 AHG55088 AHG55089 BAB63328 BAC54925 BAE78609 BAF31260 CAA05526 CAA05527 CAA46099 CAG29392 CDX10595 CDX10596 CRI06750 CRI06751 CRI06752 CRI06753 EAX03290 EAX03291 EAX03292 P13747 AB209870 BAD93107 AJ293263 CAC07212 AJ293264 CAC07213 AK098434 AK225048 AK292391 BAF85080 AK296822 BAG59393 AK298695 BAG60853 AK300906 BAG62542 AK301125 BAG62719 AK314411 AK316327 BAH14698 AY216681 AAO37688 AY221103 AAO34408 BC002578 AAH02578 BC004297 AAH04297 BC040479 AAH40479 BM791769 BX538084 CAD98008 CA439575 CD366016 DA832616 DQ891891 ABM82817 DQ895077 ABM86003 L78455 L78934 M20022 AAA52655 M31183 AAA57146 X56841 CAA40172 X64879 CAA46098 NM_005516 NP_005507
Function Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Natural killer cell mediated cytotoxicity, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Viral carcinogenesis, Herpes simplex infection

HLA-E (S-17) - sc-54608 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HLA-E (S-17): sc-54608. Western blot analysis of HLA-E expression in BJAB (A), CCRF-CEM (B) and AML-193 (C) whole cell lysates.

HLA-E (W-20) - sc-54475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HLA-E (MEM-E/08) - sc-51624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HLA-E (MEM-E/08): sc-51624. Western blot analysis of HLA-E expression in human PBL (A), BJAB (B), CCRF-CEM (C) and AML-193 (D) whole cell lysates.

HLA-E (3H2679) - sc-71262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HLA-E (3H2679): sc-71262. Western blot analysis of HLA-E expression in CCRF-CEM whole cell lysate.

HLA-E (MEM-E/02) - sc-51621 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HLA-E (MEM-E/02): sc-51621. Western blot analysis of HLA-E expression in K-562 (A), BJAB (B), human PBL (C) and HL-60 (D) whole cell lysates.

HLA-E (MEM-E/06) - sc-51622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HLA-E (MEM-E/06): sc-51622. Western blot analysis of HLA-E expression in human PBL (A), BJAB (B) and CCRF-CEM (C) whole cell lysates.

Anti-HLA E antibody - ab88090 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
FACS analysis of negative control 293 cells (Black) and HLA E expressing 293 cells (Green) using ab88090.

Anti-HLA E antibody - ab135826 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HLA E antibody (ab135826) at 1/100 dilution + MDA-MB231 lysate at 35 µg

Anti-HLA E antibody - ab171902 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HLA E antibody (ab171902) at 1 µg/mlLane 1 : HLA E transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-HLA E antibody [3D12HLA-E] - Low endotoxin, Azide free - ab171264 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3D12HLA-E

Anti-HLA E antibody [MEM-E/02] - ab2216 from Abcam

Prices $400.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/02
IHC image of ab2216 staining in human tonsil formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab2216, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-HLA E antibody [MEM-E/06] - ab3984 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/06

Anti-HLA E antibody [MEM-E/07] - ab11820 from Abcam

Prices $400.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/07
ab11820 staining HLA E in Human endothelial cell line by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100 and blocked with 5% BSA for 2 hours at 4°C. Samples were incubated with primary antibody (1/100 in 5% BSA in PBS with 0.1% Triton X-100) for 1 hour at 4°C. An undiluted FITC-conjugated Goat anti-mouse polyclonal was used as the secondary antibody.See Abreview

Anti-HLA E antibody [MEM-E/07] (Biotin) - ab99871 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/07

Anti-HLA E antibody [MEM-E/08] - ab11821 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/08
ab11821 staining HLA E in Human K562 cells by Flow Cytometry. The sample was incubated with the primary antibody, (1/50), for 1 hour at 24°C. Ab6785(1/100) was used as secondary antibody. Gating Strategy: Isotrope controlSee Abreview

Anti-HLA-E Antibody - LS-C37367 from LifeSpan Bioscience

Prices $575.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody (Azide-free) - LS-C37368 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody - LS-C68079 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody - LS-C68078 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody - LS-C68077 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody - LS-C68080 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HLA-E Antibody (clone MEM-E/02) - LS-C121956 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone MEM-E/02

Anti-HLA-E Antibody (clone MEM-E/08) - LS-C46065 from LifeSpan Bioscience

Prices $280.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/08

Anti-HLA-E Antibody (clone MEM-E/07, Biotin) - LS-C112626 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/07

Anti-HLA-E Antibody (clone MEM-E/02) - LS-C188232 from LifeSpan Bioscience

Prices $575.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone MEM-E/02
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