Gene Symbol | HMGN1 |
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Entrez Gene | 3150 |
Alt Symbol | HMG14 |
Species | Human |
Gene Type | protein-coding |
Description | high mobility group nucleosome binding domain 1 |
Other Description | high mobility group nucleosome-binding domain-containing protein 1|high-mobility group (nonhistone chromosomal) protein 14|high-mobility group nucleosome binding 1|high-mobility group nucleosome binding domain 1|non-histone chromosomal protein HMG-14|nonhistone chromosomal protein HMG-14 |
Swissprots | Q3KQR8 P05114 |
Accessions | AAA52677 CAB90453 EAX09650 EAX09651 EAX09652 EAX09653 EAX09654 EAX09655 EAX09656 P05114 AB209245 BAD92482 AK056033 BAB71078 AK130775 AK315410 AL582106 BC000075 AAH00075 BC023984 AAH23984 BC070153 AAH70153 BC070154 AAH70154 BC071643 AAH71643 BC072672 AAH72672 BC106080 AAI06081 BC107741 AAI07742 BE779939 BT007337 AAP36001 DQ891741 ABM82667 DQ894919 ABM85845 J02621 AAA52676 XM_011529543 XP_011527845 XM_011529544 XP_011527846 XM_011529545 XP_011527847 XM_011529546 XP_011527848 XM_011529547 XP_011527849 XM_011529548 XP_011527850 XM_011529549 XP_011527851 NM_004965 NP_004956 |
Function | Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus. |
Top Pathways | Herpes simplex infection |
HMGN1 (D1I5O) Rabbit mAb - 12734 from Cell Signaling Technology
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HMGN1 Antibody - 5692 from Cell Signaling Technology
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HMG-14 (A-20) - sc-19075 from Santa Cruz Biotechnology
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HMG-14 (M-70) - sc-292737 from Santa Cruz Biotechnology
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HMG-14 (N-15) - sc-19074 from Santa Cruz Biotechnology
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p-HMG-14 (15.Ser 21) - sc-135762 from Santa Cruz Biotechnology
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p-HMG-14 (91.Ser 21) - sc-135763 from Santa Cruz Biotechnology
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Anti-HMG14 antibody - ab114127 from Abcam
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Anti-HMG14 antibody - ab63358 from Abcam
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Anti-HMG14 antibody - N-terminal - ab171762 from Abcam
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Anti-HMGN1 / HMG14 Antibody (aa36-85) IHC-plus⢠- LS-B3496 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, AP) - LS-C258649 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, APC) - LS-C258650 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, Biotin) - LS-C258651 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, FITC) - LS-C258652 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, Azide-free, HRP) - LS-C258653 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30, PE) - LS-C258654 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa10-59) - LS-C117950 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (phospho-Ser21) - LS-C199068 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa1-30) - LS-C322011 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody - LS-C340905 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody - LS-C341951 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa50-92) - LS-C289114 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody (aa14-100) - LS-C294508 from LifeSpan Bioscience
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Anti-HMGN1 / HMG14 Antibody - LS-C332022 from LifeSpan Bioscience
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