| Gene Symbol |
HMGN1
|
| Entrez Gene |
3150
|
| Alt Symbol |
HMG14
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
high mobility group nucleosome binding domain 1
|
| Other Description |
high mobility group nucleosome-binding domain-containing protein 1|high-mobility group (nonhistone chromosomal) protein 14|high-mobility group nucleosome binding 1|high-mobility group nucleosome binding domain 1|non-histone chromosomal protein HMG-14|nonhistone chromosomal protein HMG-14
|
| Swissprots |
Q3KQR8 P05114
|
| Accessions |
AAA52677 CAB90453 EAX09650 EAX09651 EAX09652 EAX09653 EAX09654 EAX09655 EAX09656 P05114 AB209245 BAD92482 AK056033 BAB71078 AK130775 AK315410 AL582106 BC000075 AAH00075 BC023984 AAH23984 BC070153 AAH70153 BC070154 AAH70154 BC071643 AAH71643 BC072672 AAH72672 BC106080 AAI06081 BC107741 AAI07742 BE779939 BT007337 AAP36001 DQ891741 ABM82667 DQ894919 ABM85845 J02621 AAA52676 XM_011529543 XP_011527845 XM_011529544 XP_011527846 XM_011529545 XP_011527847 XM_011529546 XP_011527848 XM_011529547 XP_011527849 XM_011529548 XP_011527850 XM_011529549 XP_011527851 NM_004965 NP_004956
|
| Function |
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.
|
| Top Pathways |
Herpes simplex infection
|
