| Gene Symbol |
MLLT4
|
| Entrez Gene |
4301
|
| Alt Symbol |
AF6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
|
| Other Description |
ALL1-fused gene from chromosome 6 protein|afadin|protein AF-6
|
| Swissprots |
Q5TIG7 O75088 O75089 Q9NU92 P55196 Q5TIG6 O75087 Q59FP0 Q9NSN7
|
| Accessions |
BAA32483 BAA32484 BAA32485 EAW47480 EAW47481 EAW47482 EAW47483 EAW47484 EAW47485 EAW47486 P55196 AB209420 BAD92657 AB621809 BAK64145 AF085836 AI271860 AK055689 AK091815 AL161973 CAB82312 BC014505 AAH14505 BC156048 AAI56049 BC156934 AAI56935 BE503462 BE645141 BF732725 BQ646972 BX649158 CA503365 D60168 DA200453 DB079271 S82521 AAB37466 U02478 AAC50059 XM_005266996 XP_005267053 XM_005266997 XP_005267054 XM_006715491 XP_006715554 XM_006715492 XP_006715555 XM_006715493 XP_006715556 XM_006715494 XP_006715557 XM_011535840 XP_011534142 XM_011535841 XP_011534143 XM_011535842 XP_011534144 XM_011535843 XP_011534145 NM_001040000 NP_001035089 NM_001207008 NP_001193937 NM_001291964 NP_001278893 NM_001040001 NM_005936
|
| Function |
Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.
|
| Subcellular Location |
Cell junction, adherens junction. Note=Not found at cell-matrix AJs.
|
| Top Pathways |
Adherens junction, Tight junction, Leukocyte transendothelial migration, cAMP signaling pathway, Rap1 signaling pathway
|