| Gene Symbol |
SHMT2
|
| Entrez Gene |
100009293
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
serine hydroxymethyltransferase 2 (mitochondrial)
|
| Other Description |
SHMT|glycine hydroxymethyltransferase|serine hydroxymethyltransferase, mitochondrial|serine methylase
|
| Swissprots |
P14519 P79219
|
| Accessions |
P14519 X91902 CAA62998 NM_001082405 NP_001075874
|
| Function |
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Cyanoamino acid metabolism, Biosynthesis of amino acids, Carbon metabolism
|