Gene Symbol | SHMT2 |
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Entrez Gene | 100009293 |
Alt Symbol | - |
Species | Rabbit |
Gene Type | protein-coding |
Description | serine hydroxymethyltransferase 2 (mitochondrial) |
Other Description | SHMT|glycine hydroxymethyltransferase|serine hydroxymethyltransferase, mitochondrial|serine methylase |
Swissprots | P14519 P79219 |
Accessions | P14519 X91902 CAA62998 NM_001082405 NP_001075874 |
Function | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250}. Mitochondrion inner membrane {ECO:0000250}. |
Top Pathways | Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Cyanoamino acid metabolism, Biosynthesis of amino acids, Carbon metabolism |
Recombinant Rabbit Serine hydroxymethyltransferase, mitochondrial(SHMT2) - CSB-YP021274RB CSB-EP021274RB CSB-BP021274RB CSB-MP021274RB from Cusabio
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Serine hydroxymethyltransferase, mitochondrial (SHMT2), Recombinant Protein - MBS952530 from MyBioSource
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