Nmnat3

Gene Symbol Nmnat3
Entrez Gene 74080
Alt Symbol 4933408N02Rik, PNAT3
Species Mouse
Gene Type protein-coding
Description nicotinamide nucleotide adenylyltransferase 3
Other Description NMN adenylyltransferase 3|NMN/NaMN adenylyltransferase 3|naMN adenylyltransferase 1|naMN adenylyltransferase 3|nicotinamide mononucleotide adenylyltransferase 3|nicotinamide-nucleotide adenylyltransferase 3|nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3|nicotinate-nucleotide adenylyltransferase 1|nicotinate-nucleotide adenylyltransferase 3
Swissprots Q99JR6 Q58E37
Accessions EDL20981 EDL20982 EDL20983 Q99JR6 AK016744 AK040783 AK041526 BAE20591 AK041897 BAE20611 BC005737 AAH05737 BC092086 AAH92086 XM_006511502 XP_006511565 XM_006511503 XP_006511566 XM_006511504 XP_006511567 XM_006511505 XP_006511568 XM_006511506 XP_006511569 XM_006511507 XP_006511570 XM_011242826 XP_011241128 XM_011242827 XP_011241129 NM_144533 NP_653116
Function Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury. {ECO:0000269|PubMed:16914673}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:16914673}.
Top Pathways Nicotinate and nicotinamide metabolism

NMNAT-3 (B-9) - sc-398848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NMNAT-3 (B-9): sc-398848. Western blot analysis of NMNAT-3 expression in non-transfected: sc-117752 (A) and mouse NMNAT-3 transfected: sc-122083 (B) 293T whole cell lysates and mouse heart tissue extract (C).

NMNAT-3 (C-19) - sc-55866 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMNAT-3 (C-19): sc-55866. Western blot analysis of NMNAT-3 expression in non-transfected: sc-117752 (A) and mouse NMNAT-3 transfected: sc-122083 (B) 293T whole cell lysates.

NMNAT-3 (L-15) - sc-55871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMNAT-3 (L-15): sc-55871. Western blot analysis of NMNAT-3 expression in non-transfected: sc-117752 (A) and mouse transfected: sc-122083 (B) 293T whole cell lysates.

NMNAT-3 (V-14) - sc-55875 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMNAT-3 (V-14): sc-55875. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and membrane staining of cells in glomeruli and cells in tubules.

Anti-NMNAT3 antibody - ab121030 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-NMNAT3 antibody (ab121030) at 0.5 µg/ml + Mouse heart lysate at 35 µgdeveloped using the ECL technique

Anti-Nmnat3 antibody produced in goat - SAB2501843 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Nmnat3: <B>Cat. No. SAB2501843</B>: (0.5 μg/mL) staining of Mouse Heart lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Nmnat3-mouse-Antibody-internal-region - AF3590a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3590a (0.5 µg/ml) staining of Mouse Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Goat anti-Nmnat3 (mouse) middle region Antibody (OAEB02842) - OAEB02842 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NMNAT3 antibody - AP31405PU-N from Acris Antibodies

Prices $310.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AP31405PU-N NMNAT3 antibody  staining of Mouse Heart lysate at 0.5 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-NMNAT3 Antibody - AC21-2541 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (AMCA) - AC21-2541-01 from Abcore

Prices $495.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (AP) - AC21-2541-02 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (APC) - AC21-2541-03 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (APC-Cy5.5) - AC21-2541-04 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (APC-Cy7) - AC21-2541-05 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Avidin) - AC21-2541-06 from Abcore

Prices $519.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Biotin) - AC21-2541-07 from Abcore

Prices $519.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (BPE) - AC21-2541-08 from Abcore

Prices $499.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Cy3) - AC21-2541-09 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Cy5) - AC21-2541-10 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Cy5.5) - AC21-2541-11 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (FITC) - AC21-2541-12 from Abcore

Prices $489.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (Glucose Oxidase) - AC21-2541-13 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (HRP) - AC21-2541-14 from Abcore

Prices $475.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NMNAT3 Antibody (PE-Cy5) - AC21-2541-15 from Abcore

Prices $539.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
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