GNAQ

Gene Symbol GNAQ
Entrez Gene 2776
Alt Symbol CMC1, G-ALPHA-q, GAQ, SWS
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein (G protein), q polypeptide
Other Description guanine nucleotide-binding protein G(q) subunit alpha|guanine nucleotide-binding protein alpha-q
Swissprots P50148 Q13462 Q9BZB9 Q6NT27 O15108 Q92471
Accessions AEV76929 AEV76930 AEV76931 CAV33030 EAW62605 EAW62606 EAW62607 EAW62608 EAW62609 EAW62610 P50148 AB073896 AF011496 AAB64301 AF329284 AAG61117 AF493896 AAM12610 AJ420425 AK055619 AK298579 BAH12817 AL832747 AM392842 CAL37720 AM393393 CAL38271 AM393764 CAL38639 BC047048 BC057777 AAH57777 BC067850 AAH67850 BC069520 AAH69520 BC075096 AAH75096 BC075097 AAH75097 CV570171 DB474490 JN184778 AEV76928 L40629 AAA99950 L76256 AAB39498 U40038 AAC50363 U43083 AAB06875 NM_002072 NP_002063
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Membrane {ECO:0000250}. Nucleus membrane {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Tissue Specificity Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level). {ECO:0000269|PubMed:21923740, ECO:0000269|PubMed:8664309}.
Top Pathways cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Huntington's disease, Oxytocin signaling pathway

G α q CRISPR/Cas9 KO Plasmid (h) - sc-400500 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q HDR Plasmid (h) - sc-400500-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q Double Nickase Plasmid (h) - sc-400500-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q Double Nickase Plasmid (h2) - sc-400500-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q CRISPR Activation Plasmid (h) - sc-400500-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q CRISPR Activation Plasmid (h2) - sc-400500-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q Lentiviral Activation Particles (h) - sc-400500-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q Lentiviral Activation Particles (h2) - sc-400500-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α q siRNA (h) - sc-35429 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G α q shRNA Plasmid (h) - sc-35429-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G α q shRNA (h) Lentiviral Particles - sc-35429-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GNAQ RNAi - H00002776-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU108431 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9409 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9409 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08198 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08198

GNAQ siRNA (Human) - CRH1846 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAQ - MBS8231287 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human GNAQ siRNA - orb262348 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAQ shRNA Plasmid (Human) - CHH1846 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GNAQ miRNA 3'UTR clone - MiUTR3H-03794 from Creative biogene

Species Reactivities Human
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