GNAQ

Gene Symbol GNAQ
Entrez Gene 2776
Alt Symbol CMC1, G-ALPHA-q, GAQ, SWS
Species Human
Gene Type protein-coding
Description guanine nucleotide binding protein (G protein), q polypeptide
Other Description guanine nucleotide-binding protein G(q) subunit alpha|guanine nucleotide-binding protein alpha-q
Swissprots P50148 Q13462 Q9BZB9 Q6NT27 O15108 Q92471
Accessions AEV76929 AEV76930 AEV76931 CAV33030 EAW62605 EAW62606 EAW62607 EAW62608 EAW62609 EAW62610 P50148 AB073896 AF011496 AAB64301 AF329284 AAG61117 AF493896 AAM12610 AJ420425 AK055619 AK298579 BAH12817 AL832747 AM392842 CAL37720 AM393393 CAL38271 AM393764 CAL38639 BC047048 BC057777 AAH57777 BC067850 AAH67850 BC069520 AAH69520 BC075096 AAH75096 BC075097 AAH75097 CV570171 DB474490 JN184778 AEV76928 L40629 AAA99950 L76256 AAB39498 U40038 AAC50363 U43083 AAB06875 NM_002072 NP_002063
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Membrane {ECO:0000250}. Nucleus membrane {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Tissue Specificity Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level). {ECO:0000269|PubMed:21923740, ECO:0000269|PubMed:8664309}.
Top Pathways cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Huntington's disease, Oxytocin signaling pathway

Gα (pan) Antibody - 3992 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from BAEC, HEK293, NIH/3T3, C6 and COS cells, using Gα (pan) Antibody.

G α q (E-17) - sc-393 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G<sub>α q</sub> (E-17): sc-393. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

G α q (K-17) - sc-26791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G<sub>α q</sub> (K-17): sc-26791. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic, membrane and nuclear staining of glandular cells.

G α q (10) - sc-136181 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
G<sub>α q</sub> (10): sc-136181. Western blot analysis of G<sub>α q</sub> expression in human platelet extract.

Anti-GNAQ antibody - ab199900 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-GNAQ antibody (ab199900) at 1/1000 dilution + Mouse brain total cell extract

Anti-GNAQ antibody [EPR17149] - ab199533 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR17149
All lanes : Anti-GNAQ antibody [EPR17149] (ab199533) at 1/1000 dilutionLane 1 : HEK293 (Human embryonic kidney) whole cell lysateLane 2 : HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysateLane 3 : HepG2 (Human liver hepatocellular carcinoma) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-GNAQ antibody - N-terminal - ab190082 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tubules labeling GNAQ with ab190082 at 10 µg/ml.

Anti-GNAQ Antibody - LS-C96192 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa51-78, AP) - LS-C235770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa147-196) - LS-C146104 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GNAQ antibody LS-C146104 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-GNAQ Antibody (aa51-78, APC) - LS-C235771 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa71-120) IHC-plus™ - LS-B5849 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GNAQ antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5849 concentration 10 ug/ml.

Anti-GNAQ Antibody (aa51-78, FITC) - LS-C235773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa51-78, Biotin) - LS-C235772 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa51-78, PE) - LS-C235774 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa51-78, Azide-free, HRP) - LS-C249088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody - LS-C307709 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GNAQ Antibody (aa51-78) - LS-C321678 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAQ Antibody (aa162-175) IHC-plus™ - LS-B6346 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-GNAQ antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6346 concentration 5 ug/ml.

Anti-GNAQ Antibody IHC-plus™ - LS-B8891 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-GNAQ antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GNAQ Antibody (aa52-78) IHC-plus™ - LS-B9083 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-GNAQ antibody IHC staining of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GNAQ Antibody (clone 3B9) - LS-C197317 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B9
GNAQ monoclonal antibody (M04), clone 3B9. Western Blot analysis of GNAQ expression in Jurkat.

GNAQ Antibody - NBP1-58311 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GNAQ Antibody [NBP1-58311] - Human Brain lysate, concentration 0.2-1 ug/ml.

GNAQ Antibody - NBP1-72047 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: GNAQ Antibody [NBP1-72047] - Staining of Pig Colon (A) and Pig Spleen (B) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

GNAQ Antibody - NBP1-31985 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GNAQ Antibody [NBP1-31985] - A. 30 ug 293T whole cell extract B. 30 ug whole cell extract of 3xFlag-human GNAQ-transfected 293T cells 10 % SDS-PAGE GNAQ antibody dilution: 1:1000
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