Gene Symbol | SH3D19 |
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Entrez Gene | 152503 |
Alt Symbol | EBP, EVE1, Kryn, SH3P19 |
Species | Human |
Gene Type | protein-coding |
Description | SH3 domain containing 19 |
Other Description | ADAM-binding protein Eve-1|EEN-binding protein|SH3 domain protein D19|SH3 domain-containing protein 19 |
Swissprots | Q9UFC8 Q8N5E7 Q32N10 Q86XB3 Q5U3B8 Q5HYK7 B7Z296 Q08EK1 |
Accessions | EAX04986 EAX04987 Q5HYK7 AK092528 BAG52566 AK128493 BAG54685 AK291025 BAF83714 AK294476 BAH11782 AL133047 CAB61374 AW263019 BC010110 AAH10110 BC032404 BC032468 AAH32468 BC045742 AAH45742 BC085613 AAH85613 BC108890 AAI08891 BC108891 AAI08892 BC108892 AAI08893 BC108893 AAI08894 BF109395 BM670337 BM831166 BX647422 CAI46052 CD675494 CF541231 DB277036 DB278138 XM_005262767 XP_005262824 XM_011531646 XP_011529948 XM_011531647 XP_011529949 XM_011531648 XP_011529950 XM_011531649 XP_011529951 NM_001009555 NP_001009555 NM_001128923 NP_001122395 NM_001128924 NP_001122396 NM_001243349 NP_001230278 |
Function | May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:14551139, ECO:0000269|PubMed:15280379, ECO:0000269|PubMed:21834987}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14551139}. Nucleus {ECO:0000269|PubMed:14551139}. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein. |
Tissue Specificity | Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes. {ECO:0000269|PubMed:15280379}. |
Human SH3D19 full length protein - ab165648 from Abcam
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Human SH3D19 protein fragment - ab165649 from Abcam
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EBP Antibody Blocking Peptide - LS-E17002 from LifeSpan Bioscience
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EBP Antibody Blocking Peptide - LS-E6774 from LifeSpan Bioscience
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EBP Antibody Blocking Peptide - LS-E9895 from LifeSpan Bioscience
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SH3D19 Antibody Blocking Peptide - LS-E24376 from LifeSpan Bioscience
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SH3D19 Antibody Blocking Peptide - LS-E24377 from LifeSpan Bioscience
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Recombinant Human SH3D19 Protein - H00152503-Q01 from Novus Biologicals
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Recombinant Human SH3D19 Protein - H00152503-P01 from Novus Biologicals
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EBP Blocking Peptide - 33R-5513 from Fitzgerald
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SH3D19 - H00152503-P01-10 from Acris Antibodies
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SH3D19 - H00152503-P01-25 from Acris Antibodies
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SH3D19 - H00152503-Q01-10 from Acris Antibodies
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SH3D19 - H00152503-Q01-25 from Acris Antibodies
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SH3D19 fusion protein - ag16200 from Proteintech Group
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SH3D19 fusion protein - Ag15915 from Proteintech Group
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Recombinant Human SH3 domain-containing protein 19(SH3D19) - CSB-YP711356HU CSB-EP711356HU CSB-BP711356HU CSB-MP711356HU from Cusabio
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EBP Recombinant Protein Antigen - NBP1-85699PEP from Novus Biologicals
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SH3D19 Recombinant Protein Antigen - NBP1-84203PEP from Novus Biologicals
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EBP Peptide, Human - M34GP04686H from Creative Peptides
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SH3D19 Peptide, Human - M34GP14175H from Creative Peptides
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SH3D19 Recombinant Protein Antigen - NBP2-56246PEP from Novus Biologicals
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SH3 domain-containing protein 19 (SH3D19), Recombinant Protein - MBS1462690 from MyBioSource
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