Gene Symbol | SH3D19 |
---|---|
Entrez Gene | 152503 |
Alt Symbol | EBP, EVE1, Kryn, SH3P19 |
Species | Human |
Gene Type | protein-coding |
Description | SH3 domain containing 19 |
Other Description | ADAM-binding protein Eve-1|EEN-binding protein|SH3 domain protein D19|SH3 domain-containing protein 19 |
Swissprots | Q9UFC8 Q8N5E7 Q32N10 Q86XB3 Q5U3B8 Q5HYK7 B7Z296 Q08EK1 |
Accessions | EAX04986 EAX04987 Q5HYK7 AK092528 BAG52566 AK128493 BAG54685 AK291025 BAF83714 AK294476 BAH11782 AL133047 CAB61374 AW263019 BC010110 AAH10110 BC032404 BC032468 AAH32468 BC045742 AAH45742 BC085613 AAH85613 BC108890 AAI08891 BC108891 AAI08892 BC108892 AAI08893 BC108893 AAI08894 BF109395 BM670337 BM831166 BX647422 CAI46052 CD675494 CF541231 DB277036 DB278138 XM_005262767 XP_005262824 XM_011531646 XP_011529948 XM_011531647 XP_011529949 XM_011531648 XP_011529950 XM_011531649 XP_011529951 NM_001009555 NP_001009555 NM_001128923 NP_001122395 NM_001128924 NP_001122396 NM_001243349 NP_001230278 |
Function | May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:14551139, ECO:0000269|PubMed:15280379, ECO:0000269|PubMed:21834987}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14551139}. Nucleus {ECO:0000269|PubMed:14551139}. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein. |
Tissue Specificity | Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes. {ECO:0000269|PubMed:15280379}. |
SH3D19 CRISPR/Cas9 KO Plasmid (h) - sc-414719 from Santa Cruz Biotechnology
|
||||||||
SH3D19 HDR Plasmid (h) - sc-414719-HDR from Santa Cruz Biotechnology
|
||||||||
SH3D19 Double Nickase Plasmid (h) - sc-414719-NIC from Santa Cruz Biotechnology
|
||||||||
SH3D19 Double Nickase Plasmid (h2) - sc-414719-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SH3D19 CRISPR Activation Plasmid (h) - sc-414719-ACT from Santa Cruz Biotechnology
|
||||||||
SH3D19 CRISPR Activation Plasmid (h2) - sc-414719-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SH3D19 Lentiviral Activation Particles (h) - sc-414719-LAC from Santa Cruz Biotechnology
|
||||||||
SH3D19 Lentiviral Activation Particles (h2) - sc-414719-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SH3D19 siRNA (h) - sc-88945 from Santa Cruz Biotechnology
|
||||||||
SH3D19 shRNA Plasmid (h) - sc-88945-SH from Santa Cruz Biotechnology
|
||||||||
SH3D19 shRNA (h) Lentiviral Particles - sc-88945-V from Santa Cruz Biotechnology
|
||||||||
EBP RNAi - H00010682-R01 from Novus Biologicals
|
||||||||
SH3D19 RNAi - H00152503-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU083821 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19266 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19266 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10518 from Sigma-Aldrich
|
||||||||
SH3D19 siRNA (Human) - CRJ5741 from Cohesion Biosciences
|
||||||||
SH3D19 - MBS8227205 from MyBioSource
|
||||||||
shRNA set against Human SH3D19 (NM_001009555.3) - SHH406712 from Creative biogene
|
||||||||
Human SH3D19 siRNA - orb276242 from Biorbyt
|
||||||||
SH3D19 shRNA Plasmid (Human) - CHJ5741 from Cohesion Biosciences
|
||||||||
SH3D19 miRNA 3'UTR clone - MiUTR3H-10143 from Creative biogene
|
||||||||
SH3D19 miRNA 3'UTR clone - MiUTR3H-10144 from Creative biogene
|
||||||||
SH3D19 miRNA 3'UTR clone - MiUTR3H-10145 from Creative biogene
|