| Gene Symbol |
DMBX1
|
| Entrez Gene |
127343
|
| Alt Symbol |
MBX, OTX3, PAXB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
diencephalon/mesencephalon homeobox 1
|
| Other Description |
diencephalon/mesencephalon homeobox protein 1|homeoprotein MBX|orthodenticle homolog 3|paired-like homeobox protein DMBX1
|
| Swissprots |
Q8NFW6 Q8NHD9 Q8NFW5 A6NNN2
|
| Accessions |
EAX06907 Q8NFW5 AB037699 BAC00920 AF398527 AAM90589 AF398528 AAM90590 AY726596 BC156064 AAI56065 BC156881 AAI56882 XM_011540667 XP_011538969 XM_011540668 XP_011538970 XM_011540669 XP_011538971 XM_011540670 XP_011538972 NM_147192 NP_671725 NM_172225 NP_757379
|
| Function |
Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250|UniProtKB:O35137, ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE- ProRule:PRU00138}.
|
