USP37

Gene Symbol	USP37
Entrez Gene	57695
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 37
Other Description	deubiquitinating enzyme 37|tmp_locus_50|ubiquitin carboxyl-terminal hydrolase 37|ubiquitin specific protease 37|ubiquitin thioesterase 37|ubiquitin thiolesterase 37|ubiquitin-specific-processing protease 37
Swissprots	B7ZM41 Q2KHT2 Q9HCH8 Q7Z3A5 Q53S10 B7ZM38 A2RUQ8 E9PHL3 Q86T82
Accessions	AAY14887 EAW70621 EAW70622 EAW70623 Q86T82 AB046814 BAB13420 AK095577 AK128583 AL832645 CAD89955 AM392929 CAL37807 AM393416 CAL38294 BC037389 BC050461 AAH50461 BC112901 AAI12902 BC133007 AAI33008 BC133009 AAI33010 BC144249 AAI44250 BC144252 AAI44253 BX538024 CAD97970 DB075170 XM_005246720 XP_005246777 XM_005246721 XP_005246778 XM_005246722 XP_005246779 XM_005246724 XP_005246781 XM_011511538 XP_011509840 XM_011511539 XP_011509841 XM_011511540 XP_011509842 XM_011511541 XP_011509843 XM_011511542 XP_011509844 XR_922975 NM_020935 NP_065986
Function	Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'- linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). {ECO:0000269|PubMed:21596315}.
Tissue Specificity	Expressed in brain and prostate. {ECO:0000269|PubMed:14715245}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP37 protein fragment - ab163625 from Abcam Category Protein Source Wheat germ Species Human

USP37 Antibody Blocking Peptide - LS-E4134 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP37 Antibody Blocking Peptide - LS-E20986 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human USP37 Protein - H00057695-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UBP37-Antibody-N-term-Blocking-Peptide - BP16380a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP37 Blocking Peptide - 33R-7559 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

USP37 - H00057695-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

USP37 - H00057695-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

USP37 fusion protein - ag12513 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

USP37 fusion protein - ag12543 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 37(USP37) ,partial - CSB-YP801223HU CSB-EP801223HU CSB-BP801223HU CSB-MP801223HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

USP37 - TP323407 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

USP37 Recombinant Protein Antigen - NBP1-82901PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

USP37 Peptide, Human - M34GP17180H from Creative Peptides Category Peptide Source Synthetic. Species Human

USP37 Blocking Peptide - CBP5346 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

USP37 peptide - orb382203 from Biorbyt Category Peptide Species Human, Mouse, Rat

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