| Gene Symbol |
ATP6V0D2
|
| Entrez Gene |
245972
|
| Alt Symbol |
ATP6D2, VMA6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
|
| Other Description |
V-ATPase subunit d 2|V-type proton ATPase subunit d 2|vacuolar proton pump subunit d 2
|
| Swissprots |
Q8N8Y2
|
| Accessions |
EAW91631 EAW91632 Q8N8Y2 AK096027 BAC04679 AY079172 AAL87000 BC065207 AAH65207 XM_011516955 XP_011515257 NM_152565 NP_689778
|
| Function |
Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Kidney, osteoclast and lung. {ECO:0000269|PubMed:12384298}.
|
| Top Pathways |
Lysosome, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle
|
![Western Blot: ATP6V0D2 Overexpression Lysate (Adult Normal) [NBL1-07835] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATP6V0D2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7665_ATP6V0D2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07835-img0002.jpg)