Gene Symbol | ATP6V0D2 |
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Entrez Gene | 245972 |
Alt Symbol | ATP6D2, VMA6 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 |
Other Description | V-ATPase subunit d 2|V-type proton ATPase subunit d 2|vacuolar proton pump subunit d 2 |
Swissprots | Q8N8Y2 |
Accessions | EAW91631 EAW91632 Q8N8Y2 AK096027 BAC04679 AY079172 AAL87000 BC065207 AAH65207 XM_011516955 XP_011515257 NM_152565 NP_689778 |
Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). {ECO:0000250}. |
Tissue Specificity | Kidney, osteoclast and lung. {ECO:0000269|PubMed:12384298}. |
Top Pathways | Lysosome, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle |
V-ATPase D2 CRISPR/Cas9 KO Plasmid (h) - sc-404907 from Santa Cruz Biotechnology
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V-ATPase D2 HDR Plasmid (h) - sc-404907-HDR from Santa Cruz Biotechnology
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V-ATPase D2 Double Nickase Plasmid (h) - sc-404907-NIC from Santa Cruz Biotechnology
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V-ATPase D2 Double Nickase Plasmid (h2) - sc-404907-NIC-2 from Santa Cruz Biotechnology
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V-ATPase D2 CRISPR Activation Plasmid (h) - sc-404907-ACT from Santa Cruz Biotechnology
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V-ATPase D2 CRISPR Activation Plasmid (h2) - sc-404907-ACT-2 from Santa Cruz Biotechnology
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V-ATPase D2 Lentiviral Activation Particles (h) - sc-404907-LAC from Santa Cruz Biotechnology
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V-ATPase D2 Lentiviral Activation Particles (h2) - sc-404907-LAC-2 from Santa Cruz Biotechnology
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V-ATPase D2 siRNA (h) - sc-76885 from Santa Cruz Biotechnology
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V-ATPase D2 shRNA Plasmid (h) - sc-76885-SH from Santa Cruz Biotechnology
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V-ATPase D2 shRNA (h) Lentiviral Particles - sc-76885-V from Santa Cruz Biotechnology
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ATP6V0D2 RNAi - H00245972-R02 from Novus Biologicals
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MISSION® esiRNA - EHU058091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3723 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3723 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09029 from Sigma-Aldrich
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ATP6V0D2 siRNA (Human) - CRJ6613 from Cohesion Biosciences
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ATP6V0D2 - MBS8224587 from MyBioSource
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shRNA set against Human ATP6V0D2 (NM_152565.1) - SHH243050 from Creative biogene
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shRNA set against Human ATP6V0D2(NM_152565.1) - SHG083697 from Creative biogene
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Human ATP6V0D2 siRNA - orb277114 from Biorbyt
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ATP6V0D2 shRNA Plasmid (Human) - CHJ6613 from Cohesion Biosciences
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ATP6V0D2 miRNA 3'UTR clone - MiUTR1H-00712 from Creative biogene
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