CIDEC

Gene Symbol	CIDEC
Entrez Gene	63924
Alt Symbol	CIDE-3, CIDE3, FPLD5, FSP27
Species	Human
Gene Type	protein-coding
Description	cell death-inducing DFFA-like effector c
Other Description	cell death activator CIDE-3|fat specific protein 27
Swissprots	Q67DW9 C9JMN7 Q9GZY9 Q96AQ7
Accessions	CAC09160 EAW64011 EAW64012 EAW64013 EAW64014 Q96AQ7 AF303893 AAN32612 AK024524 BAB14920 AK024530 BAB14922 AL598630 AL598731 AY364638 AAR23106 AY364640 AAQ65242 BC016851 AAH16851 CD518729 CD519587 HQ447102 ADQ31589 XM_005265374 XP_005265431 XM_005265375 XP_005265432 XM_005265376 XP_005265433 NM_001199551 NP_001186480 NM_001199552 NP_001186481 NM_001199623 NP_001186552 NM_022094 NP_071377
Function	Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulatio
Subcellular Location	Nucleus {ECO:0000250}. Endoplasmic reticulum. Lipid droplet. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites.
Tissue Specificity	Expressed mainly in adipose tissue, small intestine, heart, colon and stomach and, at lower levels, in brain, kidney and liver. {ECO:0000269|PubMed:12429024, ECO:0000269|PubMed:18334488}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CIDE C full length protein - ab188449 from Abcam Category Protein Source E. coli Species Human

Human CIDE C full length protein - ab112421 from Abcam Category Protein Source Wheat germ Species Human

Human CIDE C protein fragment - ab153478 from Abcam Category Protein Source Wheat germ Species Human

FSP27 / CIDEC Antibody Blocking Peptide - LS-E5714 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CIDEC Protein - H00063924-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human CIDEC Protein - H00063924-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CIDEC-Antibody-Center-Blocking-Peptide - BP18249c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CIDEC Protein - GTX111008-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Human CIDEC Protein - abx065846 from Abbexa Category Protein Source E.coli Species Human

CIDE-C - H00063924-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CIDE-C - H00063924-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CIDE-C - H00063924-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CIDE-C - H00063924-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CIDEC fusion protein - ag2913 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CIDEC - CIDEC-27245TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Cell Death Inducing DFFA Like Effector C (CIDEC) - RPN342Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Cell Death Inducing DFFA Like Effector C (CIDEC) - RPN342Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Cell Death Inducing DFFA Like Effector C (CIDEC) - RPN342Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Cell death activator CIDE-3(CIDEC) - CSB-YP842636HU CSB-EP842636HU CSB-BP842636HU CSB-MP842636HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CIDEC Protein - abx163731 from Abbexa Category Protein Species Human

Cell death activator CIDE-3 (CIDEC), Recombinant Protein - MBS1420914 from MyBioSource Category Protein Prices $995.00, $995.00, $1,215.00, $1,215.00, $1,505.00, $1,505.00, $1,970.00, $1,970.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Cell Death Inducing DFFA Like Effector C, Recombinant Protein - MBS2031265 from MyBioSource Category Protein Prices $195.00, $420.00, $645.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Cell Death Inducing DFFA Like Effector C (CIDEC), Recombinant Protein - MBS2018665 from MyBioSource Category Protein Prices $190.00, $410.00, $635.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Human CIDEC protein - orb259845 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Cell Death-Inducing DFFA-Like Effector C Protein (Recombinant) - abx262786 from Abbexa Category Protein

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