| Gene Symbol |
PEBP4
|
| Entrez Gene |
157310
|
| Alt Symbol |
CORK-1, CORK1, GWTM1933, HEL-S-300, PEBP-4, PRO4408, hPEBP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylethanolamine-binding protein 4
|
| Other Description |
cousin-of-RKIP 1 protein|epididymis secretory protein Li 300|protein cousin-of-RKIP 1
|
| Swissprots |
Q5EVA1 Q96S96 Q8WW74
|
| Accessions |
CAT16638 EAW63647 Q96S96 AY037148 AAK67629 AY359109 AAQ89467 AY730275 AAW56965 BC020779 AAH20779 BF853000 FJ224332 ACI46024 XM_011544413 XP_011542715 XM_011544414 XP_011542716 NM_144962 NP_659399
|
| Function |
Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. {ECO:0000269|PubMed:15302887}.
|
| Subcellular Location |
Lysosome {ECO:0000269|PubMed:15302887}.
|
| Tissue Specificity |
Ubiquitously expressed. Highly expressed in tumor cells. {ECO:0000269|PubMed:15302887}.
|