Gene Symbol | PEBP4 |
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Entrez Gene | 157310 |
Alt Symbol | CORK-1, CORK1, GWTM1933, HEL-S-300, PEBP-4, PRO4408, hPEBP4 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylethanolamine-binding protein 4 |
Other Description | cousin-of-RKIP 1 protein|epididymis secretory protein Li 300|protein cousin-of-RKIP 1 |
Swissprots | Q5EVA1 Q96S96 Q8WW74 |
Accessions | CAT16638 EAW63647 Q96S96 AY037148 AAK67629 AY359109 AAQ89467 AY730275 AAW56965 BC020779 AAH20779 BF853000 FJ224332 ACI46024 XM_011544413 XP_011542715 XM_011544414 XP_011542716 NM_144962 NP_659399 |
Function | Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization. {ECO:0000269|PubMed:15302887}. |
Subcellular Location | Lysosome {ECO:0000269|PubMed:15302887}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in tumor cells. {ECO:0000269|PubMed:15302887}. |
PEBP-4 CRISPR/Cas9 KO Plasmid (h) - sc-414764 from Santa Cruz Biotechnology
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PEBP-4 HDR Plasmid (h) - sc-414764-HDR from Santa Cruz Biotechnology
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PEBP-4 Double Nickase Plasmid (h) - sc-414764-NIC from Santa Cruz Biotechnology
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PEBP-4 Double Nickase Plasmid (h2) - sc-414764-NIC-2 from Santa Cruz Biotechnology
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PEBP-4 CRISPR Activation Plasmid (h) - sc-414764-ACT from Santa Cruz Biotechnology
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PEBP-4 CRISPR Activation Plasmid (h2) - sc-414764-ACT-2 from Santa Cruz Biotechnology
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PEBP-4 Lentiviral Activation Particles (h) - sc-414764-LAC from Santa Cruz Biotechnology
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PEBP-4 Lentiviral Activation Particles (h2) - sc-414764-LAC-2 from Santa Cruz Biotechnology
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PEBP-4 siRNA (h) - sc-77509 from Santa Cruz Biotechnology
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PEBP-4 shRNA Plasmid (h) - sc-77509-SH from Santa Cruz Biotechnology
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PEBP-4 shRNA (h) Lentiviral Particles - sc-77509-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU034541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16606 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16606 from Sigma-Aldrich
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PEBP4 siRNA (Human) - CRJ5820 from Cohesion Biosciences
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shRNA set against Human PEBP4 (NM_144962.2) - SHH373356 from Creative biogene
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Human PEBP4 siRNA - orb276321 from Biorbyt
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PEBP4 shRNA Plasmid (Human) - CHJ5820 from Cohesion Biosciences
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PEBP4 miRNA 3'UTR clone - MiUTR1H-07773 from Creative biogene
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