RORB

Gene Symbol RORB
Entrez Gene 6096
Alt Symbol NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
Species Human
Gene Type protein-coding
Description RAR-related orphan receptor B
Other Description RAR-related orphan receptor beta|nuclear receptor ROR-beta|nuclear receptor RZR-beta|nuclear receptor subfamily 1 group F member 2|retinoic acid-binding receptor beta|retinoid-related orphan receptor beta|retinoid-related orphan receptor-beta
Swissprots Q92753 Q8WX73
Accessions EAW62552 Q92753 AB307695 BAH02286 AK313431 BAG36222 AL118995 AL691650 BC051830 AAH51830 BC093772 AAH93772 BC093774 AAH93774 BM669680 BM698896 BX647070 EU446652 ABZ92181 HQ709186 ADZ17393 Y08639 CAA69929 NM_006914 NP_008845
Function Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiatio
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Top Pathways Circadian rhythm

RORβ (K-16) - sc-21354 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RORβ (K-16): sc-21354. Western blot analysis of RORβ expression in DU 145 whole cell lysate.

RORβ (I-21) - sc-21353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ROR beta antibody - ab172318 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-ROR beta antibody (ab172318) at 1/500 dilutionLane 1 : ROR beta transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgGdeveloped using the ECL technique

Anti-ROR beta antibody - ab116459 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ROR beta antibody (ab116459) at 1/100 dilution + ZR-75-1 cell line lysates at 35 µg

Anti-ROR beta antibody - ab58312 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58312 ROR beta antibody at 1ug/ml.

Anti-ROR beta antibody [EPR15552] - N-terminal - ab187657 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15552
Anti-ROR beta antibody [EPR15552] - N-terminal (ab187657) at 1/1000 dilution + HepG2 cell lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-RORB / ROR Beta Antibody (Ligand-binding Domain) IHC-plus™ - LS-A2374 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ROR Beta antibody LS-A2374 IHC of human brain, thalamus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RORB / ROR Beta Antibody (Hinge Domain) IHC-plus™ - LS-A2564 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RORB / ROR Beta antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-RORB / ROR Beta Antibody (aa329-358, AP) - LS-C268455 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa329-358, APC) - LS-C268456 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa329-358, Biotin) - LS-C268457 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa28-77) - LS-C151211 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RORB / ROR Beta antibody Western Blot of Rat Stomach.

Anti-RORB / ROR Beta Antibody (aa329-358, FITC) - LS-C268458 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa86-135) - LS-C146204 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RORB / ROR-BETA antibody LS-C146204 Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.

Anti-RORB / ROR Beta Antibody (aa329-358, Azide-free, HRP) - LS-C268459 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa329-358, PE) - LS-C268460 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (aa328-358) - LS-C324763 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RORB / ROR Beta Antibody (C-Terminus) - LS-C80236 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RORB / ROR Beta Antibody (aa1-260, clone 1B6) - LS-C340111 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RORB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RORB.

Anti-RORB / ROR Beta Antibody (aa1-260, clone 4B12) - LS-C340114 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4B12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RORB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RORB.

Anti-RORB / ROR Beta Antibody (aa1-260, clone 4B7) - LS-C340136 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4B7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RORB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RORB.

Anti-RORB / ROR Beta Antibody (aa1-260, clone 1C11) - LS-C340138 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RORB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RORB.

Anti-RORB / ROR Beta Antibody (clone 4B4) - LS-C198101 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B4
Western Blot analysis of RORB expression in transfected 293T cell line by RORB monoclonal antibody (M01), clone 4B4.Lane 1: RORB transfected lysate (Predicted MW: 52.1 KDa).Lane 2: Non-transfected lysate.

Anti-RORB / ROR Beta Antibody (aa329-358) - LS-C162679 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RORB Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RORB / ROR Beta Antibody (Hinge Domain) IHC-plus™ - LS-A5531 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ROR Beta antibody LS-A5531 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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