RORB

Gene Symbol	RORB
Entrez Gene	6096
Alt Symbol	NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
Species	Human
Gene Type	protein-coding
Description	RAR-related orphan receptor B
Other Description	RAR-related orphan receptor beta|nuclear receptor ROR-beta|nuclear receptor RZR-beta|nuclear receptor subfamily 1 group F member 2|retinoic acid-binding receptor beta|retinoid-related orphan receptor beta|retinoid-related orphan receptor-beta
Swissprots	Q92753 Q8WX73
Accessions	EAW62552 Q92753 AB307695 BAH02286 AK313431 BAG36222 AL118995 AL691650 BC051830 AAH51830 BC093772 AAH93772 BC093774 AAH93774 BM669680 BM698896 BX647070 EU446652 ABZ92181 HQ709186 ADZ17393 Y08639 CAA69929 NM_006914 NP_008845
Function	Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiatio
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Top Pathways	Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ROR beta full length protein - ab114845 from Abcam Category Protein Source Wheat germ Species Human

Human ROR beta protein fragment - ab159368 from Abcam Category Protein Source Wheat germ Species Human

RORB / ROR Beta Antibody Blocking Peptide - LS-E2929 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RORB / ROR Beta Antibody Blocking Peptide - LS-E29077 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RORB / ROR Beta Antibody Blocking Peptide - LS-E14001 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RORB / ROR Beta Antibody Blocking Peptide - LS-E28552 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RORB / ROR Beta Antibody Blocking Peptide - LS-E28568 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RORB / ROR Beta Antibody Blocking Peptide - LS-E16659 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ROR beta Protein - H00006096-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ROR beta Protein - H00006096-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RORB-Antibody-C-term-Blocking-peptide - BP14054b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ROR-beta / RORB - H00006096-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ROR-beta / RORB - H00006096-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ROR-beta / RORB - H00006096-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ROR-beta / RORB - H00006096-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RORB fusion protein - Ag11910 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RORB fusion protein - Ag11925 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human RORB - RORB-30957TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human RORB, GST-tagged - RORB-2359H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Nuclear receptor ROR-beta(RORB) - CSB-YP821694HU CSB-EP821694HU CSB-BP821694HU CSB-MP821694HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RAR-related orphan receptor B (RORB) - TP308666 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human RORB protein, MYC/DDK-tagged - RORB-2360H from Creative Biomart Category Protein Source HEK293 Species Human

RORB Peptide, Human - M34GP13472H from Creative Peptides Category Peptide Source Synthetic. Species Human

ROR beta Recombinant Protein Antigen - NBP1-82532PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nuclear receptor ROR-beta (RORB), Recombinant Protein - MBS1420315 from MyBioSource Category Protein Prices $1,250.00, $1,250.00, $1,470.00, $1,470.00, $2,045.00, $2,045.00, $2,510.00, $2,510.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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