Mzb1

Gene Symbol Mzb1
Entrez Gene 69816
Alt Symbol 2010001M09Rik, AV064572, PACAP, pERp1
Species Mouse
Gene Type protein-coding
Description marginal zone B and B1 cell-specific protein 1
Other Description marginal zone B- and B1-cell-specific protein|plasma cell-induced ER protein 1|plasma cell-induced resident ER protein|plasma cell-induced resident endoplasmic reticulum protein|proapoptotic caspase adapter protein
Swissprots Q9D8I1 Q8K2M5 D2IYS1 Q8BU13 Q6P3D3
Accessions CAH19023 CAH25960 EDK97136 EDK97137 Q9D8I1 AA866731 AK008016 BAB25410 AK088094 BAC40141 BC030674 AAH30674 BC064044 AAH64044 GQ477351 ACY74344 NM_027222 NP_081498
Function Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.
Subcellular Location Endoplasmic reticulum. Endoplasmic reticulum lumen. Secreted.
Tissue Specificity Expressed predominantly in the spleen and lymph nodes. Abundantly expressed in marginal zone B and B1 cells. High expression in mesenteric adipose tissue (MAT). Expressed also in pancreas, perigonadal adipose tissue (PAT), uterus, subcutaneous adipose tissue, heart, muscle, ovary and liver. Very low expression is detected in brown adipose tissue. In PAT, significantly higher expression in stromal-vascular cell than in adipocytes. Expressed in macrophage RAW 264.7 cell line. Down- regulated in For-knockout female MAT at 5 months (obese state) followed by steep up-regulation at 9 months (prediabetic condition) when mutants progress towards the metabolic syndrome. {ECO:0000269|PubMed:19805154, ECO:0000269|PubMed:21093319, ECO:0000269|PubMed:21688198}.

Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1), Mouse, ELISA Kit - SEB347Mu from ARP American Research Products

Category ELISA Kit
Prices $704.00
Sizes 96 t
Sensitivity 2.8pg/mL
Range 7.8-500pg/mL

Pituitary adenylate cyclase-activating polypeptide (ADCYAP1), Mouse, ELISA Kit - CSB-EL001346MO from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mouse PACAP ELISA Kit - MP0592 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Mouse PACAP(Pituitary Adenylate Cyclase Activating Polypeptide) ELISA Kit - E-EL-M0910 from Elabscience

Category ELISA Kit
Sensitivity 9.38 pg/mL
Range 15.63—1000 pg/mL

Mouse PACAP (Pituitary Adenylate Cyclase Activating Polypeptide) CLIA Kit - E-CL-M0548 from Elabscience

Category CLIA Kit
Sensitivity 4.69 pg/mL
Range Average Recovery (%)

Mouse Pituitary adenylate cyclase activating polypeptide ELISA - E03P0585 from BlueGene Biotech

Category ELISA Kit
Sensitivity 1.0 pg/mL

ELISA Kit for Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1) - SEB347Mu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 3.2pg/mL.
Range 7.813-500pg/mL The standard curve concentrations used for the ELISA's were 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.625pg/mL, 7.813pg/mL

Mouse PACAP(Pituitary Adenylate Cyclase Activating Polypeptide) ELISA Kit - E-EL-M0910 from Iwai North America Inc.

Category ELISA Kit
Prices $580.00
Sizes 1 kit
Sensitivity 9.38 pg/mL
Range 15.63~1000 pg/mL

Mouse PACAP ELISA Kit - abx054872 from Abbexa

Category ELISA Kit

Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1), Mouse, ELISA Kit - DL-ADCYAP1-Mu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Range 7.8-500 pg/mL

PACAP - EKM2518 from Nordic BioSite

Sensitivity 9.375pg/ml
Range 15.625--1000pg/ml

Mouse PACAP ELISA Kit - E063806 from Biobool

Category ELISA Kit
Sensitivity 0.1 ng/ml.

Mouse Mzb1 ELISA Kit - E090705 from Biobool

Category ELISA Kit

Mouse PACAP ELISA Kit - EMP0592 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t
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