MFGE8

Gene Symbol	MFGE8
Entrez Gene	4240
Alt Symbol	BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47
Species	Human
Gene Type	protein-coding
Description	milk fat globule-EGF factor 8 protein
Other Description	O-acetyl disialoganglioside synthase|breast epithelial antigen BA46|lactadherin|medin|sperm associated antigen 10|sperm surface protein hP47
Swissprots	Q7Z3D2 Q53FU9 B2R6M7 Q08431 Q9BTL9
Accessions	EAX02025 EAX02026 EAX02027 EAX02028 EAX02029 EAX02030 Q08431 AK095908 BAG53164 AK222735 BAD96455 AK223182 BAD96902 AK304627 BAG65408 AK310357 AK312640 BAG35524 AU134066 AY141974 AAN08508 BC003610 AAH03610 BT006948 AAP35594 BU726667 BX537974 CAD97938 EU832670 ACE87761 EU832749 ACE87081 S56151 AAB19771 U58516 AAC50549 XM_005254921 XP_005254978 XR_931838 NM_001114614 NP_001108086 NM_005928 NP_005919
Function	Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. {ECO:0000250, ECO:0000269|PubMed:19204935}.
Subcellular Location	Membrane {ECO:0000269|PubMed:19204935}; Peripheral membrane protein {ECO:0000269|PubMed:19204935}. Secreted {ECO:0000269|PubMed:19204935}.
Tissue Specificity	Mammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Milk Fat Globule 1 full length protein - ab158881 from Abcam Category Protein Source Wheat germ Species Human

Human Milk Fat Globule 1 protein fragment - ab158882 from Abcam Category Protein Source Wheat germ Species Human

MFGE8 /Lactadherin Antibody Blocking Peptide - LS-E2024 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MFG-E8 Recombinant Protein - H00004240-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

MFG-E8 Partial Recombinant Protein - H00004240-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HMFG-Antibody-C-term-Blocking-peptide - BP12888b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human MFG-E8, CF - 2767-MF-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Leu24-Cys387, with a C-terminal 6-His tag

Recombinant human Lactadherin protein (OPCA00736) - OPCA00736 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Recombinant human Lactadherin protein (OPCA00737) - OPCA00737 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human MFG-E8 protein (His Tag) - orb139338 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human MFGE8 protein - orb244373 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human MFGE8 protein - orb245358 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human MFGE8 protein - orb245357 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Lactadherin protein - 30R-3143 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

MFGE8 protein - 30R-3261 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

MFG-E8 Blocking Peptide - abx161161 from Abbexa Category Peptide Species Human, Mouse, Rat

Lactadherin - H00004240-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Lactadherin - H00004240-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Lactadherin - H00004240-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MFGE8 fusion protein - ag13621 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MFGE8, His tagged - MFGE8-7305H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human MFGE8, His-tagged - MFGE8-587H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human MFGE8, His-tagged - MFGE8-408H from Creative Biomart Category Protein Source Mouse NS0 Cells Species Human

Recombinant Milk Fat Globule EGF Factor 8 (MFGE8) - RPB286Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Milk Fat Globule EGF Factor 8 (MFGE8) - RPB286Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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