Gene Symbol | ZDHHC21 |
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Entrez Gene | 340481 |
Alt Symbol | 9130404H11Rik, DHHC-21, DHHC21, DNZ1, HSPC097 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, DHHC-type containing 21 |
Other Description | palmitoyltransferase ZDHHC21|probable palmitoyltransferase ZDHHC21|zinc finger DHHC domain-containing protein 21|zinc finger, DHHC domain containing 21 |
Swissprots | D3DRI7 Q5VWG1 A8KA95 Q8IVQ6 |
Accessions | EAW58692 EAW58693 Q8IVQ6 AF161360 AAF28920 AK026322 AK096860 AK124263 AK127313 AK292960 BAF85649 BC042439 BC042558 AAH42558 HQ447981 ADQ32464 XM_006716760 XP_006716823 XM_011517851 XP_011516153 XM_011517852 XP_011516154 XM_011517853 XP_011516155 XM_011517854 XP_011516156 XM_011517855 XP_011516157 NM_178566 NP_848661 |
Function | Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus {ECO:0000250}. |
ZDHHC21 CRISPR/Cas9 KO Plasmid (h) - sc-406104 from Santa Cruz Biotechnology
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ZDHHC21 HDR Plasmid (h) - sc-406104-HDR from Santa Cruz Biotechnology
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ZDHHC21 Double Nickase Plasmid (h) - sc-406104-NIC from Santa Cruz Biotechnology
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ZDHHC21 Double Nickase Plasmid (h2) - sc-406104-NIC-2 from Santa Cruz Biotechnology
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ZDHHC21 CRISPR Activation Plasmid (h) - sc-406104-ACT from Santa Cruz Biotechnology
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ZDHHC21 CRISPR Activation Plasmid (h2) - sc-406104-ACT-2 from Santa Cruz Biotechnology
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ZDHHC21 Lentiviral Activation Particles (h) - sc-406104-LAC from Santa Cruz Biotechnology
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ZDHHC21 Lentiviral Activation Particles (h2) - sc-406104-LAC-2 from Santa Cruz Biotechnology
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ZDHHC21 siRNA (h) - sc-92600 from Santa Cruz Biotechnology
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ZDHHC21 shRNA Plasmid (h) - sc-92600-SH from Santa Cruz Biotechnology
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ZDHHC21 shRNA (h) Lentiviral Particles - sc-92600-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23145 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23145 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10563 from Sigma-Aldrich
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ZDHHC21 siRNA (Human) - CRJ7347 from Cohesion Biosciences
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ZDHHC21 RNAi - H00340481-R01 from Novus Biologicals
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ZDHHC21 - MBS8217982 from MyBioSource
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shRNA set against Human ZDHHC21 (NM_178566.4) - SHH449964 from Creative biogene
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Human ZDHHC21 siRNA - orb277848 from Biorbyt
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ZDHHC21 shRNA Plasmid (Human) - CHJ7347 from Cohesion Biosciences
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ZDHHC21 miRNA 3'UTR clone - MiUTR4H-TG10049 from Creative biogene
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