Gene Symbol | SLN |
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Entrez Gene | 6588 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | sarcolipin |
Other Description | - |
Swissprots | Q6ICV3 O00631 |
Accessions | AAB86980 EAW67094 O00631 AK312097 BAG35033 BC005261 AAH05261 BC094685 AAH94685 BC104150 AAI04151 BC104185 AAI04186 BC113930 AAI13931 BC113987 AAI13988 BP233121 CR450290 CAG29286 F30315 U96094 AAB86981 NM_003063 NP_003054 |
Function | Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Required for muscle-based, non-shivering thermogenesis (By similarity). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. {ECO:0000250, ECO:0000269|PubMed:11781085, ECO:0000269|PubMed:9575189}. |
Subcellular Location | Sarcoplasmic reticulum membrane; Single-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
SLN overexpression lysate - LY418924 from Acris Antibodies
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SLN 293 Cell Lysate - 408846 from ABBIOTEC
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SLN Overexpression Lysate (Native) - NBL1-16214 from Novus Biologicals
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SLN Over-expression Lysate Product - GWB-8E13F1 from Genway Biotech
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Panoply™ Human SLN Knockdown Stable Cell Line - CSC-DC014703 from Creative biogene
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