Gene Symbol | Cyp1a2 |
---|---|
Entrez Gene | 24297 |
Alt Symbol | CYPD45, P-450d, RATCYPD45 |
Species | Rat |
Gene Type | protein-coding |
Description | cytochrome P450, family 1, subfamily a, polypeptide 2 |
Other Description | CYPIA2|Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d)|P-448|P450-D|cytochrome P-448|cytochrome P-450d|cytochrome P450 1A2|cytochrome P450, 1a2|cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d)|cytochrome P450-D |
Swissprots | Q64588 A1L120 P04799 |
Accessions | AAA41053 EDL95645 P04799 BC127476 AAI27477 FQ209607 FQ210213 FQ210219 K02422 AAA41028 M26127 X01031 CAA25516 NM_012541 NP_036673 |
Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism |
Recombinant Cytochrome P450 1A2 (CYP1A2) - RPD294Ra01 from Cloud-clone
|
||||||||||
Recombinant Rat Cytochrome P450 1A2(Cyp1a2) - CSB-YP006396RA CSB-EP006396RA CSB-BP006396RA CSB-MP006396RA from Cusabio
|
||||||||||
Cytochrome P450 1A2 Protein (Recombinant) - abx167612 from Abbexa
|
||||||||||
Recombinant Rat CYP1A2 Protein - CYP1A2-1716R from Creative Biomart
|
||||||||||
Recombinant Cytochrome P450 1A2 (CYP1A2) - RPU53124 from Biomatik
|
||||||||||
CYP1A2 Recombinant Protein (OPCD02602) - OPCD02602 from Aviva Systems Biology
|
||||||||||
Cytochrome P450 1A2 (Cyp1a2), Recombinant Protein - MBS1209912 from MyBioSource
|