| Gene Symbol |
Cyp1a2
|
| Entrez Gene |
24297
|
| Alt Symbol |
CYPD45, P-450d, RATCYPD45
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 1, subfamily a, polypeptide 2
|
| Other Description |
CYPIA2|Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d)|P-448|P450-D|cytochrome P-448|cytochrome P-450d|cytochrome P450 1A2|cytochrome P450, 1a2|cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d)|cytochrome P450-D
|
| Swissprots |
Q64588 A1L120 P04799
|
| Accessions |
AAA41053 EDL95645 P04799 BC127476 AAI27477 FQ209607 FQ210213 FQ210219 K02422 AAA41028 M26127 X01031 CAA25516 NM_012541 NP_036673
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Top Pathways |
Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450, Tryptophan metabolism
|