| Gene Symbol |
LILRA5
|
| Entrez Gene |
353514
|
| Alt Symbol |
CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
|
| Other Description |
CD85 antigen-like family member F|immunoglobulin-like transcript 11 protein|leukocyte Ig-like receptor 9|leukocyte immunoglobulin-like receptor 9|leukocyte immunoglobulin-like receptor subfamily A member 5|leukocyte immunoglobulin-like receptor subfamily A member 5 soluble|leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7
|
| Swissprots |
A6NHI3 A6NI73
|
| Accessions |
A6NI73 CAK32290 EAW72226 EAW72227 EAW72228 EAW72229 AF212842 AAF73849 AF324830 AAK52451 AF499916 AAN27925 AF499917 AAN27926 AF499918 AAN27927 AF499919 AAN27928 BC148658 AAI48659 BC153203 AAI53204 EU915611 ACK56077 EU915612 ACK56078 NM_021250 NP_067073 NM_181879 NP_870994 NM_181985 NP_871714 NM_181986 NP_871715
|
| Function |
May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. {ECO:0000269|PubMed:16675463}.
|
| Subcellular Location |
Isoform 3: Secreted.
|
| Tissue Specificity |
Expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Among leukocytes, monocytes and neutrophils express the highest level. Expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level). {ECO:0000269|PubMed:12393390}.
|
| Top Pathways |
Osteoclast differentiation
|