| Gene Symbol | LILRA5 |
|---|---|
| Entrez Gene | 353514 |
| Alt Symbol | CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9 |
| Species | Human |
| Gene Type | protein-coding |
| Description | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| Other Description | CD85 antigen-like family member F|immunoglobulin-like transcript 11 protein|leukocyte Ig-like receptor 9|leukocyte immunoglobulin-like receptor 9|leukocyte immunoglobulin-like receptor subfamily A member 5|leukocyte immunoglobulin-like receptor subfamily A member 5 soluble|leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7 |
| Swissprots | A6NHI3 A6NI73 |
| Accessions | A6NI73 CAK32290 EAW72226 EAW72227 EAW72228 EAW72229 AF212842 AAF73849 AF324830 AAK52451 AF499916 AAN27925 AF499917 AAN27926 AF499918 AAN27927 AF499919 AAN27928 BC148658 AAI48659 BC153203 AAI53204 EU915611 ACK56077 EU915612 ACK56078 NM_021250 NP_067073 NM_181879 NP_870994 NM_181985 NP_871714 NM_181986 NP_871715 |
| Function | May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. {ECO:0000269|PubMed:16675463}. |
| Subcellular Location | Isoform 3: Secreted. |
| Tissue Specificity | Expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Among leukocytes, monocytes and neutrophils express the highest level. Expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level). {ECO:0000269|PubMed:12393390}. |
| Top Pathways | Osteoclast differentiation |
ILT-11 CRISPR/Cas9 KO Plasmid (h) - sc-408001 from Santa Cruz Biotechnology
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ILT-11 HDR Plasmid (h) - sc-408001-HDR from Santa Cruz Biotechnology
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ILT-11 Double Nickase Plasmid (h) - sc-408001-NIC from Santa Cruz Biotechnology
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ILT-11 Double Nickase Plasmid (h2) - sc-408001-NIC-2 from Santa Cruz Biotechnology
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ILT-11 CRISPR Activation Plasmid (h) - sc-408001-ACT from Santa Cruz Biotechnology
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ILT-11 CRISPR Activation Plasmid (h2) - sc-408001-ACT-2 from Santa Cruz Biotechnology
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ILT-11 Lentiviral Activation Particles (h) - sc-408001-LAC from Santa Cruz Biotechnology
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ILT-11 Lentiviral Activation Particles (h2) - sc-408001-LAC-2 from Santa Cruz Biotechnology
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ILT-11 siRNA (h) - sc-105621 from Santa Cruz Biotechnology
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ILT-11 shRNA Plasmid (h) - sc-105621-SH from Santa Cruz Biotechnology
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ILT-11 shRNA (h) Lentiviral Particles - sc-105621-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11710 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11710 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02966 from Sigma-Aldrich
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LILRA5 siRNA (Human) - CRJ7594 from Cohesion Biosciences
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shRNA set against Human LILRA5 (NM_021250.2) - SHH330279 from Creative biogene
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Human LILRA5 siRNA - orb278095 from Biorbyt
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LILRA5 shRNA Plasmid (Human) - CHJ7594 from Cohesion Biosciences
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LILRA5 miRNA 3'UTR clone - MiUTR1H-05671 from Creative biogene
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LILRA5 miRNA 3'UTR clone - MiUTR3H-08170 from Creative biogene
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LILRA5 miRNA 3'UTR clone - MiUTR3H-08171 from Creative biogene
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