| Gene Symbol |
INTS1
|
| Entrez Gene |
26173
|
| Alt Symbol |
INT1, NET28
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
integrator complex subunit 1
|
| Other Description |
-
|
| Swissprots |
Q8N201 Q6NT70 Q96D36 A6NJ44 Q9P2A8 Q9NTD1 Q8WV40 Q6UX74 Q9Y3W8
|
| Accessions |
EAL23941 EAL23942 Q8N201 AB037861 BAA92678 AI935093 AK128368 AL050110 CAB43278 AL137358 CAB70710 AY358482 AAQ88846 BC004286 AAH04286 BC013367 AAH13367 BC018777 AAH18777 BC069262 AAH69262 BF346658 BK005720 DAA05720 BM547069 BM553299 BX324321 DB113520 XM_011515260 XP_011513562 XM_011515261 XP_011513563 XM_011515262 XP_011513564 NM_001080453 NP_001073922
|
| Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
|
| Subcellular Location |
Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
![Western Blot: INTS1 Overexpression Lysate (Adult Normal) [NBP2-08335] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for INTS1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5211_INTS1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08335-img0001.jpg)