Gene Symbol | INTS1 |
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Entrez Gene | 26173 |
Alt Symbol | INT1, NET28 |
Species | Human |
Gene Type | protein-coding |
Description | integrator complex subunit 1 |
Other Description | - |
Swissprots | Q8N201 Q6NT70 Q96D36 A6NJ44 Q9P2A8 Q9NTD1 Q8WV40 Q6UX74 Q9Y3W8 |
Accessions | EAL23941 EAL23942 Q8N201 AB037861 BAA92678 AI935093 AK128368 AL050110 CAB43278 AL137358 CAB70710 AY358482 AAQ88846 BC004286 AAH04286 BC013367 AAH13367 BC018777 AAH18777 BC069262 AAH69262 BF346658 BK005720 DAA05720 BM547069 BM553299 BX324321 DB113520 XM_011515260 XP_011513562 XM_011515261 XP_011513563 XM_011515262 XP_011513564 NM_001080453 NP_001073922 |
Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
Subcellular Location | Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
INTS1 CRISPR/Cas9 KO Plasmid (h) - sc-409878 from Santa Cruz Biotechnology
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INTS1 HDR Plasmid (h) - sc-409878-HDR from Santa Cruz Biotechnology
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INTS1 Double Nickase Plasmid (h) - sc-409878-NIC from Santa Cruz Biotechnology
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INTS1 Double Nickase Plasmid (h2) - sc-409878-NIC-2 from Santa Cruz Biotechnology
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INTS1 CRISPR Activation Plasmid (h) - sc-409878-ACT from Santa Cruz Biotechnology
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INTS1 CRISPR Activation Plasmid (h2) - sc-409878-ACT-2 from Santa Cruz Biotechnology
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INTS1 Lentiviral Activation Particles (h) - sc-409878-LAC from Santa Cruz Biotechnology
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INTS1 Lentiviral Activation Particles (h2) - sc-409878-LAC-2 from Santa Cruz Biotechnology
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INTS1 siRNA (h) - sc-89497 from Santa Cruz Biotechnology
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INTS1 shRNA Plasmid (h) - sc-89497-SH from Santa Cruz Biotechnology
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INTS1 shRNA (h) Lentiviral Particles - sc-89497-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU123521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10709 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10709 from Sigma-Aldrich
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INTS1 siRNA (Human) - CRH8748 from Cohesion Biosciences
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INTS1 - MBS8224515 from MyBioSource
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shRNA set against Human INTS1 (NM_001080453.2) - SHH319929 from Creative biogene
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shRNA set against Human INTS1(NM_001080453.2) - SHL179550 from Creative biogene
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Human INTS1 siRNA - orb269250 from Biorbyt
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INTS1 shRNA Plasmid (Human) - CHH8748 from Cohesion Biosciences
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INTS1 miRNA 3'UTR clone - MiUTR1H-04968 from Creative biogene
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