| Gene Symbol |
EMB
|
| Entrez Gene |
133418
|
| Alt Symbol |
GP70
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
embigin
|
| Other Description |
embigin homolog
|
| Swissprots |
Q6PCB8 B7Z902 B7Z6S3
|
| Accessions |
EAW54852 EAW54853 EAW54854 Q6PCB8 AK300860 BAH13359 AK304226 BAH14138 BC059398 AAH59398 DC309453 JF432793 ADZ16010 U52054 XM_011543146 XP_011541448 NM_198449 NP_940851
|
| Function |
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Localizes to the neuromuscular junctions. {ECO:0000250}.
|