Gene Symbol | EMB |
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Entrez Gene | 133418 |
Alt Symbol | GP70 |
Species | Human |
Gene Type | protein-coding |
Description | embigin |
Other Description | embigin homolog |
Swissprots | Q6PCB8 B7Z902 B7Z6S3 |
Accessions | EAW54852 EAW54853 EAW54854 Q6PCB8 AK300860 BAH13359 AK304226 BAH14138 BC059398 AAH59398 DC309453 JF432793 ADZ16010 U52054 XM_011543146 XP_011541448 NM_198449 NP_940851 |
Function | Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Localizes to the neuromuscular junctions. {ECO:0000250}. |
Embigin CRISPR/Cas9 KO Plasmid (h) - sc-408321 from Santa Cruz Biotechnology
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Embigin HDR Plasmid (h) - sc-408321-HDR from Santa Cruz Biotechnology
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Embigin Double Nickase Plasmid (h) - sc-408321-NIC from Santa Cruz Biotechnology
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Embigin Double Nickase Plasmid (h2) - sc-408321-NIC-2 from Santa Cruz Biotechnology
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Embigin CRISPR Activation Plasmid (h) - sc-408321-ACT from Santa Cruz Biotechnology
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Embigin CRISPR Activation Plasmid (h2) - sc-408321-ACT-2 from Santa Cruz Biotechnology
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Embigin Lentiviral Activation Particles (h) - sc-408321-LAC from Santa Cruz Biotechnology
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Embigin Lentiviral Activation Particles (h2) - sc-408321-LAC-2 from Santa Cruz Biotechnology
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Embigin siRNA (h) - sc-91726 from Santa Cruz Biotechnology
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Embigin shRNA Plasmid (h) - sc-91726-SH from Santa Cruz Biotechnology
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Embigin shRNA (h) Lentiviral Particles - sc-91726-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU112531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7832 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7832 from Sigma-Aldrich
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EMB siRNA (Human) - CRJ5115 from Cohesion Biosciences
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EMB - MBS8228828 from MyBioSource
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shRNA set against Human EMB (NM_198449.2) - SHH285377 from Creative biogene
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EMB shRNA Plasmid (Human) - CHJ5115 from Cohesion Biosciences
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EMB miRNA 3'UTR clone - MiUTR4H-TG03066 from Creative biogene
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