Gene Symbol | GABRQ |
---|---|
Entrez Gene | 55879 |
Alt Symbol | THETA |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, theta |
Other Description | GABA(A) receptor subunit theta|gamma-aminobutyric acid receptor subunit theta |
Swissprots | Q9UN88 A6NFN1 Q32MB4 Q9NZK8 |
Accessions | EAW99424 Q9UN88 AF144648 AAD51172 AF189259 AAF70380 BC109210 AAI09211 BC109211 AAI09212 U47334 AAC50559 XM_011531184 XP_011529486 NM_018558 NP_061028 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |