Gene Symbol | GABRQ |
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Entrez Gene | 55879 |
Alt Symbol | THETA |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, theta |
Other Description | GABA(A) receptor subunit theta|gamma-aminobutyric acid receptor subunit theta |
Swissprots | Q9UN88 A6NFN1 Q32MB4 Q9NZK8 |
Accessions | EAW99424 Q9UN88 AF144648 AAD51172 AF189259 AAF70380 BC109210 AAI09211 BC109211 AAI09212 U47334 AAC50559 XM_011531184 XP_011529486 NM_018558 NP_061028 |
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
GABA A Rθ CRISPR/Cas9 KO Plasmid (h) - sc-406766 from Santa Cruz Biotechnology
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GABA A Rθ HDR Plasmid (h) - sc-406766-HDR from Santa Cruz Biotechnology
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GABA A Rθ Double Nickase Plasmid (h) - sc-406766-NIC from Santa Cruz Biotechnology
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GABA A Rθ Double Nickase Plasmid (h2) - sc-406766-NIC-2 from Santa Cruz Biotechnology
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GABA A Rθ CRISPR Activation Plasmid (h) - sc-406766-ACT from Santa Cruz Biotechnology
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GABA A Rθ CRISPR Activation Plasmid (h2) - sc-406766-ACT-2 from Santa Cruz Biotechnology
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GABA A Rθ Lentiviral Activation Particles (h) - sc-406766-LAC from Santa Cruz Biotechnology
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GABA A Rθ Lentiviral Activation Particles (h2) - sc-406766-LAC-2 from Santa Cruz Biotechnology
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GABA A Rθ siRNA (h) - sc-105384 from Santa Cruz Biotechnology
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GABA A Rθ shRNA Plasmid (h) - sc-105384-SH from Santa Cruz Biotechnology
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GABA A Rθ shRNA (h) Lentiviral Particles - sc-105384-V from Santa Cruz Biotechnology
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GABA-A R theta RNAi - H00055879-R01 from Novus Biologicals
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MISSION® esiRNA - EHU159051 from Sigma-Aldrich
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MISSION® esiRNA - EHU092041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2438 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2438 from Sigma-Aldrich
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GABRQ siRNA (Human) - CRJ0988 from Cohesion Biosciences
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GABRQ - MBS8239798 from MyBioSource
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GABAA Rθ CRISPR/Cas9 KO Plasmid (h2) - sc-406766-KO-2 from Santa Cruz Biotechnology
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GABAA Rθ HDR Plasmid (h2) - sc-406766-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GABRQ (NM_018558.2) - SHH298617 from Creative biogene
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Human GABRQ siRNA - orb271489 from Biorbyt
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GABRQ shRNA Plasmid (Human) - CHJ0988 from Cohesion Biosciences
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GABRQ miRNA 3'UTR clone - MiUTR3H-02704 from Creative biogene
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