Gene Symbol | Psme1 |
---|---|
Entrez Gene | 29630 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) activator subunit 1 |
Other Description | 11S regulator complex subunit alpha|PA28a|PA28alpha|REG-alpha|activator of multicatalytic protease subunit 1|protease (prosome, macropain) 28 subunit, alpha|proteasome (prosome, macropain) 28 subunit, alpha|proteasome activator 28 subunit alpha|proteasome activator complex subunit 1 |
Swissprots | Q63797 |
Accessions | EDM14241 Q63797 BC060574 AAH60574 D45249 BAA08206 FQ216423 FQ219304 FQ220175 FQ224986 FQ226855 FQ228562 FQ230622 FQ233032 FQ233635 FQ233859 NM_017264 NP_058960 |
Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
Top Pathways | Proteasome, Antigen processing and presentation |