| Gene Symbol |
Psme1
|
| Entrez Gene |
29630
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) activator subunit 1
|
| Other Description |
11S regulator complex subunit alpha|PA28a|PA28alpha|REG-alpha|activator of multicatalytic protease subunit 1|protease (prosome, macropain) 28 subunit, alpha|proteasome (prosome, macropain) 28 subunit, alpha|proteasome activator 28 subunit alpha|proteasome activator complex subunit 1
|
| Swissprots |
Q63797
|
| Accessions |
EDM14241 Q63797 BC060574 AAH60574 D45249 BAA08206 FQ216423 FQ219304 FQ220175 FQ224986 FQ226855 FQ228562 FQ230622 FQ233032 FQ233635 FQ233859 NM_017264 NP_058960
|
| Function |
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
|
| Top Pathways |
Proteasome, Antigen processing and presentation
|