Gene Symbol | EFNB1 |
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Entrez Gene | 1947 |
Alt Symbol | CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2 |
Species | Human |
Gene Type | protein-coding |
Description | ephrin-B1 |
Other Description | EFL-3|ELK ligand|LERK-2|eph-related receptor tyrosine kinase ligand 2|ligand of eph-related kinase 2 |
Swissprots | D3DVU0 P98172 |
Accessions | EAX05370 EAX05371 P98172 AK311197 BC016649 AAH16649 BC052979 AAH52979 BM972960 BU172498 CB132233 DQ891817 ABM82743 DQ895005 ABM85931 L37361 AAA52369 U09303 AAB41127 U09304 AAA53093 NM_004429 NP_004420 |
Function | Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas. |
Top Pathways | Axon guidance |
Phospho-Ephrin B (Tyr324/329) Antibody - 3481 from Cell Signaling Technology
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ephrin-B1 (A-20) - sc-1011 from Santa Cruz Biotechnology
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ephrin-B1 (H-70) - sc-20723 from Santa Cruz Biotechnology
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ephrin-B1/2/3 (C-18) - sc-910 from Santa Cruz Biotechnology
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p-ephrin-B1 (Tyr 317) - sc-135691 from Santa Cruz Biotechnology
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p-ephrin-B1 (Tyr 331) - sc-135692 from Santa Cruz Biotechnology
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Anti-Ephrin B (phospho Y298) antibody - ab33069 from Abcam
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Anti-Ephrin B (phospho Y317) antibody - ab33473 from Abcam
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Anti-Ephrin B (phospho Y324) antibody - ab138468 from Abcam
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Anti-Ephrin B (phospho Y329) antibody - ab111487 from Abcam
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Anti-Ephrin B (phospho Y330) antibody - ab51118 from Abcam
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Anti-Ephrin B (phospho Y330) antibody - C-terminal - ab195844 from Abcam
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Anti-Ephrin B (phospho Y331) antibody - ab32586 from Abcam
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Anti-Ephrin B antibody - ab55352 from Abcam
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Anti-Ephrin B antibody - ab61161 from Abcam
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Anti-Ephrin B1 (phospho Y317) antibody - ab138401 from Abcam
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Anti-Ephrin B1 (phospho Y331) antibody - ab30563 from Abcam
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Anti-Ephrin B1 antibody - ab99029 from Abcam
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Anti-EFNB1 / Ephrin B1 Antibody - LS-C6551 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (Internal) - LS-C6548 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (aa136-347) - LS-C188982 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (aa88-116, AP) - LS-C213667 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (phospho-Tyr317) - LS-C53451 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (aa88-116, APC) - LS-C213668 from LifeSpan Bioscience
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Anti-EFNB1 / Ephrin B1 Antibody (aa88-116, Azide-free, HRP) - LS-C213671 from LifeSpan Bioscience
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