Gene Symbol | EFNB1 |
---|---|
Entrez Gene | 1947 |
Alt Symbol | CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2 |
Species | Human |
Gene Type | protein-coding |
Description | ephrin-B1 |
Other Description | EFL-3|ELK ligand|LERK-2|eph-related receptor tyrosine kinase ligand 2|ligand of eph-related kinase 2 |
Swissprots | D3DVU0 P98172 |
Accessions | EAX05370 EAX05371 P98172 AK311197 BC016649 AAH16649 BC052979 AAH52979 BM972960 BU172498 CB132233 DQ891817 ABM82743 DQ895005 ABM85931 L37361 AAA52369 U09303 AAB41127 U09304 AAA53093 NM_004429 NP_004420 |
Function | Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas. |
Top Pathways | Axon guidance |
ephrin-B1 CRISPR/Cas9 KO Plasmid (h) - sc-400873 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 HDR Plasmid (h) - sc-400873-HDR from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 Double Nickase Plasmid (h) - sc-400873-NIC from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 Double Nickase Plasmid (h2) - sc-400873-NIC-2 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 CRISPR Activation Plasmid (h) - sc-400873-ACT from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 CRISPR Activation Plasmid (h2) - sc-400873-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 Lentiviral Activation Particles (h) - sc-400873-LAC from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 Lentiviral Activation Particles (h2) - sc-400873-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 siRNA (h) - sc-39436 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 shRNA Plasmid (h) - sc-39436-SH from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 shRNA (h) Lentiviral Particles - sc-39436-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU035421 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN7699 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7699 from Sigma-Aldrich
|
||||||||
EFNB1 siRNA (Human) - CRH1344 from Cohesion Biosciences
|
||||||||
EFNB1 - MBS8203563 from MyBioSource
|
||||||||
ephrin-B1 CRISPR/Cas9 KO Plasmid (h2) - sc-400873-KO-2 from Santa Cruz Biotechnology
|
||||||||
ephrin-B1 HDR Plasmid (h2) - sc-400873-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human EFNB1 (NM_004429.4) - SHH283681 from Creative biogene
|
||||||||
Human EFNB1 siRNA - orb261846 from Biorbyt
|
||||||||
EFNB1 shRNA Plasmid (Human) - CHH1344 from Cohesion Biosciences
|
||||||||
EFNB1 miRNA 3'UTR clone - MiUTR3H-02508 from Creative biogene
|