| Gene Symbol | EFNB1 |
|---|---|
| Entrez Gene | 1947 |
| Alt Symbol | CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ephrin-B1 |
| Other Description | EFL-3|ELK ligand|LERK-2|eph-related receptor tyrosine kinase ligand 2|ligand of eph-related kinase 2 |
| Swissprots | D3DVU0 P98172 |
| Accessions | EAX05370 EAX05371 P98172 AK311197 BC016649 AAH16649 BC052979 AAH52979 BM972960 BU172498 CB132233 DQ891817 ABM82743 DQ895005 ABM85931 L37361 AAA52369 U09303 AAB41127 U09304 AAA53093 NM_004429 NP_004420 |
| Function | Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas. |
| Top Pathways | Axon guidance |