UROS

Gene Symbol UROS
Entrez Gene 7390
Alt Symbol UROIIIS
Species Human
Gene Type protein-coding
Description uroporphyrinogen III synthase
Other Description hydroxymethylbilane hydrolyase|uroporphyrinogen-III cosynthase|uroporphyrinogen-III synthase
Swissprots B2RC13 Q9H2T1 P10746 D3DRF7
Accessions EAW49221 EAW49222 EAW49223 EAW49224 EAW49225 EAW49226 EAW49227 EAW49228 EAW49229 P10746 AF230665 AAG36795 AK314896 BAG37410 BC002573 AAH02573 BC004338 AAH04338 DQ891936 ABM82862 DQ895123 ABM86049 DR156879 J03824 AAA60273 XM_005270137 XP_005270194 XM_005270138 XP_005270195 XM_005270139 XP_005270196 XM_005270140 XP_005270197 XM_005270141 XP_005270198 XM_006717960 XP_006718023 XM_011540126 XP_011538428 XM_011540127 XP_011538429 XR_246103 XR_945809 XR_945810 NM_000375 NP_000366
Function Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:11112350}.
Top Pathways Porphyrin and chlorophyll metabolism

UROS CRISPR/Cas9 KO Plasmid (h) - sc-411052 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS HDR Plasmid (h) - sc-411052-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS Double Nickase Plasmid (h) - sc-411052-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS Double Nickase Plasmid (h2) - sc-411052-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS CRISPR Activation Plasmid (h) - sc-411052-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS CRISPR Activation Plasmid (h2) - sc-411052-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS Lentiviral Activation Particles (h) - sc-411052-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS Lentiviral Activation Particles (h2) - sc-411052-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UROS siRNA (h) - sc-61760 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UROS shRNA Plasmid (h) - sc-61760-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UROS shRNA (h) Lentiviral Particles - sc-61760-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UROS RNAi - H00007390-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU020591 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22545 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22545 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01785 from Sigma-Aldrich

Category miRNA

UROS siRNA (Human) - CRH5056 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UROS - MBS828657 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UROS (NM_000375.2) - SHH441069 from Creative biogene

Category siRNA
Species Reactivities Human

UROS shRNA Plasmid (Human) - CHH5056 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UROS miRNA 3'UTR clone - MiUTR3H-08840 from Creative biogene

Species Reactivities Human
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